Rhodium‐Catalyzed Regioselective C7‐Functionalization of <i>N</i>‐Pivaloylindoles
書誌事項
- 公開日
- 2015-10-29
- 権利情報
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- http://onlinelibrary.wiley.com/termsAndConditions#vor
- DOI
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- 10.1002/anie.201508117
- 公開者
- Wiley
この論文をさがす
説明
<jats:title>Abstract</jats:title><jats:p>An efficient rhodium‐catalyzed method for direct CH functionalization at the C7 position of a wide range of indoles has been developed. Good to excellent yields of alkenylation products were observed with acrylates, styrenes, and vinyl phenyl sulfones, whereas the saturated alkylation products were obtained in good yield with α,β‐unsaturated ketones. Both the <jats:italic>N</jats:italic>‐pivaloyl directing group and the rhodium catalyst proved to be crucial for high regioselectivity and conversion.</jats:p>
収録刊行物
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- Angewandte Chemie International Edition
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Angewandte Chemie International Edition 55 (1), 321-325, 2015-10-29
Wiley