Autonomic Nervous Control of Uveal Blood Flow

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書誌事項

公開日
1962-09
権利情報
  • http://onlinelibrary.wiley.com/termsAndConditions#vor
DOI
  • 10.1111/j.1748-1716.1962.tb02482.x
公開者
Wiley

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説明

<jats:title>Abstract</jats:title><jats:p>A study was made of the influence of the autonomic nervous system and its transmitter substances on the vascular resistance <jats:italic>UVR</jats:italic> influencing the blood flow through the uvea in rabbits and cats. The results were analyzed and interpreted on the basis of an α‐, β‐and γ‐receptor concept. Electrical stimulation of the cervical sympathetics produced considerable increments in <jats:italic>UVR</jats:italic> in both species, indicating α‐receptors. Isopropylnoradrenaline given intraarterially did not change <jats:italic>UVR</jats:italic> in any of the species. Neither did i. a. administration of adrenaline after pretreatment with dibenzyline. There was then no indication for β‐receptors. Acetylcholine given i. a. reduced <jats:italic>UVR</jats:italic> in both the species indicating γ‐receptors. These receptors could be activated neither by stimulation of the ciliary ganglion (experiments only in cats) nor by stimulation of the cervical sympathetics. The γ‐receptors therefore seem not to be innervated by any of these routes. Results indicate that the flow reactions in the choroid were about the same as those within the anterior uvea.</jats:p>

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