Advancements in Next-Generation Sequencing

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  • Shawn E. Levy
    HudsonAlpha Institute for Biotechnology, Huntsville, Alabama 35806;,
  • Richard M. Myers
    HudsonAlpha Institute for Biotechnology, Huntsville, Alabama 35806;,

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<jats:p> The term next-generation sequencing is almost a decade old, but it remains the colloquial way to describe highly parallel or high-output sequencing methods that produce data at or beyond the genome scale. Since the introduction of these technologies, the number of applications and methods that leverage the power of genome-scale sequencing has increased at an exponential pace. This review highlights recent concepts, technologies, and methods from next-generation sequencing to illustrate the breadth and depth of the applications and research areas that are driving progress in genomics. </jats:p>

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