Cardiovascular effects of particulate air pollution exposure: time course and underlying mechanisms

  • J. P. Langrish
    BHF/University Centre for Cardiovascular Science University of Edinburgh Edinburgh UK
  • J. Bosson
    Department of Public Health and Clinical Medicine, Division of Medicine/Respiratory Medicine Umeå University Umeå Sweden
  • J. Unosson
    Department of Public Health and Clinical Medicine, Division of Medicine/Respiratory Medicine Umeå University Umeå Sweden
  • A. Muala
    Department of Public Health and Clinical Medicine, Division of Medicine/Respiratory Medicine Umeå University Umeå Sweden
  • D. E. Newby
    BHF/University Centre for Cardiovascular Science University of Edinburgh Edinburgh UK
  • N. L. Mills
    BHF/University Centre for Cardiovascular Science University of Edinburgh Edinburgh UK
  • A. Blomberg
    Department of Public Health and Clinical Medicine, Division of Medicine/Respiratory Medicine Umeå University Umeå Sweden
  • T. Sandström
    Department of Public Health and Clinical Medicine, Division of Medicine/Respiratory Medicine Umeå University Umeå Sweden

説明

<jats:title>Abstract</jats:title><jats:sec><jats:title>Objective</jats:title><jats:p>Air pollution is now recognized as an important independent risk factor for cardiovascular morbidity and mortality and may be responsible for up to 3 million premature deaths each year worldwide. The mechanisms underlying the observed effects are poorly understood but are likely to be multifactorial. Here, we review the acute and chronic effects of air pollution exposure on the cardiovascular system and discuss how these effects may explain the observed increases in cardiovascular morbidity and mortality.</jats:p></jats:sec>

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