Mitochondria and cells produce reactive oxygen species in virtual anaerobiosis: relevance to ceramide‐induced apoptosis
書誌事項
- 公開日
- 1998-07-03
- 権利情報
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- http://onlinelibrary.wiley.com/termsAndConditions#vor
- DOI
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- 10.1016/s0014-5793(98)00688-7
- 公開者
- Wiley
この論文をさがす
説明
<jats:p>Observations of apoptosis in virtual anaerobiosis have raised doubts on the significance of reactive oxygen species in the cascade of events of programmed cell death. This work presents evidence that cells and mitochondrial preparations produce similar levels of hydrogen peroxide under either aerobic or virtually anaerobic conditions. These levels are relevant to the increased production of radicals induced by a ceramide analog that promotes apoptosis. This ceramide acts at center o of mitochondrial complex III.</jats:p>
収録刊行物
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- FEBS Letters
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FEBS Letters 430 (3), 338-342, 1998-07-03
Wiley