Synthesis, DNA/protein binding, molecular docking, DNA cleavage and in vitro anticancer activity of nickel(<scp>ii</scp>) bis(thiosemicarbazone) complexes
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- Jebiti Haribabu
- Department of Chemistry
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- Kumaramangalam Jeyalakshmi
- Department of Chemistry
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- Yuvaraj Arun
- Organic Chemistry Division
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- Nattamai S. P. Bhuvanesh
- Department of Chemistry
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- Paramasivan Thirumalai Perumal
- Organic Chemistry Division
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- Ramasamy Karvembu
- Department of Chemistry
書誌事項
- 公開日
- 2015
- DOI
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- 10.1039/c5ra04498g
- 公開者
- Royal Society of Chemistry (RSC)
説明
<p>Cytotoxic nickel(<sc>ii</sc>) complexes with an N-substituted isatin thiosemicarbazone were synthesized and their interaction with CT DNA and BSA protein was investigated, which was supported by molecular docking studies.</p>
収録刊行物
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- RSC Advances
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RSC Advances 5 (57), 46031-46049, 2015
Royal Society of Chemistry (RSC)
