書誌事項
- 公開日
- 2007-08
- 権利情報
-
- https://www.cambridge.org/core/terms
- DOI
-
- 10.1192/bjp.bp.106.028829
- 公開者
- Royal College of Psychiatrists
この論文をさがす
説明
<jats:sec><jats:title>Background</jats:title><jats:p>Epidemiological studies of schizophrenia suggest that this disorder has a substantial genetic component. Cognitive and social abilities, as well as the volumes of brain regions involved in emotion processing, have been found to be distributed along a continuum when comparing patients, siblings and controls, with siblings showing intermediate scores.</jats:p></jats:sec><jats:sec><jats:title>Aims</jats:title><jats:p>To establish whether facial expression recognition is impaired in unaffected siblings of patients.</jats:p></jats:sec><jats:sec><jats:title>Method</jats:title><jats:p>Emotion and gender recognition were evaluated in a three-group pre–post study design in drugnaive patients with first-episode schizophrenia (<jats:italic>n</jats:italic>=40) and their unaffected siblings (<jats:italic>n</jats:italic>=30) compared with controls (<jats:italic>n</jats:italic>=26).</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Patients and their healthy siblings showed impaired emotion recognition but normal gender recognition compared with controls. Patients' performance did not improve despite effective clinical stabilisation.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>Impaired performance in healthy siblings and time stability in patients provides evidence of impairment of facial emotion recognition as an actual phenotype of schizophrenia.</jats:p></jats:sec>
収録刊行物
-
- British Journal of Psychiatry
-
British Journal of Psychiatry 191 (2), 126-130, 2007-08
Royal College of Psychiatrists