Advanced chronic heart failure: A position statement from the Study Group on Advanced Heart Failure of the Heart Failure Association of the European Society of Cardiology
-
- Marco Metra
- Section of Cardiovascular Diseases, Department of Experimental and Applied Medicine University of Brescia Italy
-
- Piotr Ponikowski
- Department of Cardiology Military Hospital Wroclaw Poland
-
- Kenneth Dickstein
- Cardiology Division, University of Bergen Stavanger University Hospital Stavanger Norway
-
- John J.V. McMurray
- Department of Cardiology, Western Infirmary Glasgow UK
-
- Antonello Gavazzi
- Department of Cardiology Ospedali Riuniti di Bergamo Bergamo Italy
-
- Claes‐Hakan Bergh
- Department of Cardiology Sahlgrenska University Hospital/Sahlgrenska Göteborg Sweden
-
- Alan G. Fraser
- Department of Cardiology, Wales Heart Research Institute University of Wales College of Medicine Cardiff UK
-
- Tiny Jaarsma
- Department of Cardiology, Programme Coördinator COACH University Hospital Groningen Groningen The Netherlands
-
- Antonis Pitsis
- Department of Cardiac Surgery St. Luke's Hospital Panorama Thessaloniki Greece
-
- Paul Mohacsi
- Swiss Cardiovascular Center Bern Head Heart Failure & Cardiac Transplant. University Hospital (Inselspital) Bern Switzerland
-
- Michael Böhm
- Innere Medizin III, Universitätskliniken des Saarlandes Homburg/Saar Germany
-
- Stefan Anker
- Applied Cachexia Research, Department of Cardiology Charité Campus Virchow‐Klinikum Berlin Germany
-
- Henry Dargie
- Cardiac Department Western Infirmary Glasgow Scotland UK
-
- Dirk Brutsaert
- Department of Cardiology, A.Z. Middellheim Hospital Univ. of Antwerp Antwerp Belgium
-
- Michel Komajda
- Département de Cardiologie Pitié Salpêtrière Hospital Paris Cedex 13 France
Description
<jats:title>Abstract</jats:title><jats:p>Therapy has improved the survival of heart failure (HF) patients. However, many patients progress to advanced chronic HF (ACHF). We propose a practical clinical definition and describe the characteristics of this condition.</jats:p><jats:p>Patients that are generally recognised as ACHF often exhibit the following characteristics: 1) severe symptoms (NYHA class III to IV); 2) episodes with clinical signs of fluid retention and/or peripheral hypoperfusion; 3) objective evidence of severe cardiac dysfunction, shown by at least one of the following: left ventricular ejection fraction<30%, pseudonormal or restrictive mitral inflow pattern at Doppler‐echocardiography; high left and/or right ventricular filling pressures; elevated B‐type natriuretic peptides; 4) severe impairment of functional capacity demonstrated by either inability to exercise, a 6‐minute walk test distance<300 m or a peak oxygen uptake<12–14 ml/kg/min; 5) history of >1 HF hospitalisation in the past 6 months; 6) presence of all the previous features despite optimal therapy. This definition identifies a group of patients with compromised quality of life, poor prognosis, and a high risk of clinical events. These patients deserve effective therapeutic options and should be potential targets for future clinical research initiatives.</jats:p>
Journal
-
- European Journal of Heart Failure
-
European Journal of Heart Failure 9 (6-7), 684-694, 2007-05-11
Wiley
- Tweet
Details 詳細情報について
-
- CRID
- 1361699995281446272
-
- ISSN
- 18790844
- 13889842
-
- Data Source
-
- Crossref