The Impact of Aging on Cardio and Cerebrovascular Diseases

  • Carmine Izzo
    Departement of Medicine and Surgery, University of Salerno, 84081 Salerno, Italy
  • Albino Carrizzo
    Vascular Physiopathology Unit, IRCCS Neuromed, 86077 Pozzilli, Italy
  • Antonia Alfano
    Heart Department, A.O.U. “San Giovanni di Dio e Ruggi d’Aragona”, 84131 Salerno, Italy
  • Nicola Virtuoso
    Department of Cardiovascular Medicine, A.O.U. Federico II, 80131 Naples, Italy
  • Mario Capunzo
    Departement of Medicine and Surgery, University of Salerno, 84081 Salerno, Italy
  • Mariaconsiglia Calabrese
    Rehabilitation Department, A.O.U. “San Giovanni di Dio e Ruggi d’Aragona”, 84131 Salerno, Italy
  • Eros De Simone
    Heart Department, A.O.U. “San Giovanni di Dio e Ruggi d’Aragona”, 84131 Salerno, Italy
  • Sebastiano Sciarretta
    Vascular Physiopathology Unit, IRCCS Neuromed, 86077 Pozzilli, Italy
  • Giacomo Frati
    Vascular Physiopathology Unit, IRCCS Neuromed, 86077 Pozzilli, Italy
  • Marco Oliveti
    Departement of Medicine and Surgery, University of Salerno, 84081 Salerno, Italy
  • Antonio Damato
    Vascular Physiopathology Unit, IRCCS Neuromed, 86077 Pozzilli, Italy
  • Mariateresa Ambrosio
    Vascular Physiopathology Unit, IRCCS Neuromed, 86077 Pozzilli, Italy
  • Francesco De Caro
    Departement of Medicine and Surgery, University of Salerno, 84081 Salerno, Italy
  • Paolo Remondelli
    Departement of Medicine and Surgery, University of Salerno, 84081 Salerno, Italy
  • Carmine Vecchione
    Departement of Medicine and Surgery, University of Salerno, 84081 Salerno, Italy

説明

<jats:p>A growing number of evidences report that aging represents the major risk factor for the development of cardio and cerebrovascular diseases. Understanding Aging from a genetic, biochemical and physiological point of view could be helpful to design a better medical approach and to elaborate the best therapeutic strategy to adopt, without neglecting all the risk factors associated with advanced age. Of course, the better way should always be understanding risk-to-benefit ratio, maintenance of independence and reduction of symptoms. Although improvements in treatment of cardiovascular diseases in the elderly population have increased the survival rate, several studies are needed to understand the best management option to improve therapeutic outcomes. The aim of this review is to give a 360° panorama on what goes on in the fragile ecosystem of elderly, why it happens and what we can do, right now, with the tools at our disposal to slow down aging, until new discoveries on aging, cardio and cerebrovascular diseases are at hand.</jats:p>

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