Helical Porous Protein Mimics Self-Assembled from Amphiphilic Dendritic Dipeptides*

  • Virgil Percec
    ARoy & Diana Vagelos Laboratories, Department of Chemistry, Laboratory for Research on the Structure of Matter, University of Pennsylvania, Philadelphia, PA 19104-6323, USA.
  • Andrés Dulcey
    ARoy & Diana Vagelos Laboratories, Department of Chemistry, Laboratory for Research on the Structure of Matter, University of Pennsylvania, Philadelphia, PA 19104-6323, USA.
  • Yoshiko Miura
    ARoy & Diana Vagelos Laboratories, Department of Chemistry, Laboratory for Research on the Structure of Matter, University of Pennsylvania, Philadelphia, PA 19104-6323, USA.
  • Mihai Peterca
    BDepartment of Physics and Astronomy, Laboratory for Research on the Structure of Matter, University of Pennsylvania, Philadelphia, PA 19104-6396, USA.
  • Monica Ilies
    ARoy & Diana Vagelos Laboratories, Department of Chemistry, Laboratory for Research on the Structure of Matter, University of Pennsylvania, Philadelphia, PA 19104-6323, USA.
  • Paul A. Heiney
    BDepartment of Physics and Astronomy, Laboratory for Research on the Structure of Matter, University of Pennsylvania, Philadelphia, PA 19104-6396, USA.
  • Ulrica Edlund
    ARoy & Diana Vagelos Laboratories, Department of Chemistry, Laboratory for Research on the Structure of Matter, University of Pennsylvania, Philadelphia, PA 19104-6323, USA.

書誌事項

公開日
2005-06-14
権利情報
  • https://doi.org/10.1071/journalslicense
DOI
  • 10.1071/ch05092
公開者
CSIRO Publishing

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説明

<jats:p>This manuscript reports the synthesis and the self-assembly of (4-3,4,5-3,5)nG2-CH2-Boc-l-Tyr-l-Ala-OMe dendritic dipeptides (n = 12, 16). These dendritic dipeptides self-assemble both in solution and in solid states into helical porous supramolecular columns that mimic porous transmembrane proteins. These supramolecular assemblies provide also a new class of tubular supramolecular polymers.</jats:p>

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