Human Milk and Allergic Diseases: An Unsolved Puzzle

  • Daniel Munblit
    Department of Paediatrics, Imperial College London, London W2 1NY, UK
  • Diego Peroni
    The In-FLAME Global Network, an Affiliate of the World Universities Network (WUN), West New York, NJ 07093, USA
  • Alba Boix-Amorós
    The In-FLAME Global Network, an Affiliate of the World Universities Network (WUN), West New York, NJ 07093, USA
  • Peter Hsu
    The In-FLAME Global Network, an Affiliate of the World Universities Network (WUN), West New York, NJ 07093, USA
  • Belinda Land
    Nutricia Research, 3584 CT Utrecht, The Netherlands
  • Melvin Gay
    The In-FLAME Global Network, an Affiliate of the World Universities Network (WUN), West New York, NJ 07093, USA
  • Anastasia Kolotilina
    Faculty of Pediatrics, I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia
  • Chrysanthi Skevaki
    The In-FLAME Global Network, an Affiliate of the World Universities Network (WUN), West New York, NJ 07093, USA
  • Robert Boyle
    Department of Paediatrics, Imperial College London, London W2 1NY, UK
  • Maria Collado
    The In-FLAME Global Network, an Affiliate of the World Universities Network (WUN), West New York, NJ 07093, USA
  • Johan Garssen
    Nutricia Research, 3584 CT Utrecht, The Netherlands
  • Donna Geddes
    The In-FLAME Global Network, an Affiliate of the World Universities Network (WUN), West New York, NJ 07093, USA
  • Ralph Nanan
    Charles Perkins Centre Nepean, University of Sydney, Sydney, NSW 2747, Australia
  • Carolyn Slupsky
    Department of Nutrition, University of California, Davis, CA 95616-5270, USA
  • Ganesa Wegienka
    The In-FLAME Global Network, an Affiliate of the World Universities Network (WUN), West New York, NJ 07093, USA
  • Anita Kozyrskyj
    Department of Pediatrics, University of Alberta, Edmonton, AB T6G 1C9, Canada
  • John Warner
    Department of Paediatrics, Imperial College London, London W2 1NY, UK

書誌事項

公開日
2017-08-17
権利情報
  • https://creativecommons.org/licenses/by/4.0/
DOI
  • 10.3390/nu9080894
公開者
MDPI AG

説明

<jats:p>There is conflicting evidence on the protective role of breastfeeding in relation to the development of allergic sensitisation and allergic disease. Studies vary in methodology and definition of outcomes, which lead to considerable heterogeneity. Human milk composition varies both within and between individuals, which may partially explain conflicting data. It is known that human milk composition is very complex and contains variable levels of immune active molecules, oligosaccharides, metabolites, vitamins and other nutrients and microbial content. Existing evidence suggests that modulation of human breast milk composition has potential for preventing allergic diseases in early life. In this review, we discuss associations between breastfeeding/human milk composition and allergy development.</jats:p>

収録刊行物

  • Nutrients

    Nutrients 9 (8), 894-, 2017-08-17

    MDPI AG

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