Syndrome of Inappropriate Antidiuretic Hormone Associated with Escitalopram Therapy

DOI Web Site 被引用文献1件

書誌事項

公開日
2006-06
権利情報
  • https://www.cambridge.org/core/terms
DOI
  • 10.1017/s1092852900014620
公開者
Cambridge University Press (CUP)

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説明

<jats:title>ABSTRACT</jats:title><jats:p>Escitalopram is the selective serotonin reuptake inhibitor (SSRI) most recently approved for use in the United States. It is structurally related to citalopram, but is felt to have a more tolerable side-effect profile than its parent compound. Side effects are not generally serious and include headache, diarrhea, and nausea. While hyponatremia and the syndrome of inappropriate antidiuretic hormone (SIADH) have been associated with treatment with other SSRIs, there has only been one case of escitalopram-induced SIADH reported in the literature to date. We now report another case of a patient who developed SIADH after being treated with escitalopram for 4 weeks. The patient's hyponatremia improved following the discontinuation of escitalopram. Clinicians should be aware of this uncommon but significant side effect of SSRIs and monitor high-risk patients for the development of SIADH.</jats:p>

収録刊行物

  • CNS Spectrums

    CNS Spectrums 11 (6), 429-432, 2006-06

    Cambridge University Press (CUP)

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