Structure of an Agonist-Bound Human A <sub>2A</sub> Adenosine Receptor

  • Fei Xu
    Department of Molecular Biology, Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Huixian Wu
    Department of Molecular Biology, Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Vsevolod Katritch
    Skaggs School of Pharmacy and Pharmaceutical Sciences and San Diego Supercomputer Center, University of California, San Diego, La Jolla, CA 92093, USA.
  • Gye Won Han
    Department of Molecular Biology, Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Kenneth A. Jacobson
    Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD 20892, USA.
  • Zhan-Guo Gao
    Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD 20892, USA.
  • Vadim Cherezov
    Department of Molecular Biology, Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Raymond C. Stevens
    Department of Molecular Biology, Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

書誌事項

公開日
2011-04-15
権利情報
  • http://www.sciencemag.org/site/feature/contribinfo/prep/license.xhtml
DOI
  • 10.1126/science.1202793
公開者
American Association for the Advancement of Science (AAAS)

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説明

<jats:p>Changes associated with conformationally selective agonist binding shed light on G protein–coupled receptor activation.</jats:p>

収録刊行物

  • Science

    Science 332 (6027), 322-327, 2011-04-15

    American Association for the Advancement of Science (AAAS)

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