High-resolution sub-cellular imaging by correlative NanoSIMS and electron microscopy of amiodarone internalisation by lung macrophages as evidence for drug-induced phospholipidosis
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- Haibo Jiang
- Centre for Microscopy
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- Melissa K. Passarelli
- National Centre of Excellence in Mass Spectrometry Imaging (NiCE-MSI)
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- Peter M. G. Munro
- Institute of Ophthalmology
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- Matt R. Kilburn
- Centre for Microscopy
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- Andrew West
- GlaxoSmithKline
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- Colin T. Dollery
- GlaxoSmithKline
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- Ian S. Gilmore
- National Centre of Excellence in Mass Spectrometry Imaging (NiCE-MSI)
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- Paulina D. Rakowska
- National Centre of Excellence in Mass Spectrometry Imaging (NiCE-MSI)
抄録
<p>Correlative NanoSIMS and EM imaging of amiodarone-treated macrophages shows the internalisation of the drug at a sub-cellular level.</p>
収録刊行物
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- Chemical Communications
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Chemical Communications 53 (9), 1506-1509, 2017
Royal Society of Chemistry (RSC)