Detection of Lipid-Core Plaques by Intracoronary Near-Infrared Spectroscopy Identifies High Risk of Periprocedural Myocardial Infarction

DOI Web Site 被引用文献14件
  • James A. Goldstein
    From the Department of Cardiovascular Medicine, William Beaumont Hospital, Royal Oak, MI (J.A.G., S.R.D., C.L.G.); Pinnacle Health, Moffitt Heart and Vascular Group, Wormleysburg, PA (B.M.); Veterans Affairs North Texas Healthcare System and University of Texas Southwestern Medical Center at Dallas, Dallas, TX (E.B.); Scottsdale Heart Group, Scottsdale Healthcare Hospital, Scottsdale, AZ (D.G.R.); Heart and Vascular Center, Medical University of South Carolina, Charleston, SC (E.R.P., D.H.S.); the...
  • Brijeshwar Maini
    From the Department of Cardiovascular Medicine, William Beaumont Hospital, Royal Oak, MI (J.A.G., S.R.D., C.L.G.); Pinnacle Health, Moffitt Heart and Vascular Group, Wormleysburg, PA (B.M.); Veterans Affairs North Texas Healthcare System and University of Texas Southwestern Medical Center at Dallas, Dallas, TX (E.B.); Scottsdale Heart Group, Scottsdale Healthcare Hospital, Scottsdale, AZ (D.G.R.); Heart and Vascular Center, Medical University of South Carolina, Charleston, SC (E.R.P., D.H.S.); the...
  • Simon R. Dixon
    From the Department of Cardiovascular Medicine, William Beaumont Hospital, Royal Oak, MI (J.A.G., S.R.D., C.L.G.); Pinnacle Health, Moffitt Heart and Vascular Group, Wormleysburg, PA (B.M.); Veterans Affairs North Texas Healthcare System and University of Texas Southwestern Medical Center at Dallas, Dallas, TX (E.B.); Scottsdale Heart Group, Scottsdale Healthcare Hospital, Scottsdale, AZ (D.G.R.); Heart and Vascular Center, Medical University of South Carolina, Charleston, SC (E.R.P., D.H.S.); the...
  • Emmanouil S. Brilakis
    From the Department of Cardiovascular Medicine, William Beaumont Hospital, Royal Oak, MI (J.A.G., S.R.D., C.L.G.); Pinnacle Health, Moffitt Heart and Vascular Group, Wormleysburg, PA (B.M.); Veterans Affairs North Texas Healthcare System and University of Texas Southwestern Medical Center at Dallas, Dallas, TX (E.B.); Scottsdale Heart Group, Scottsdale Healthcare Hospital, Scottsdale, AZ (D.G.R.); Heart and Vascular Center, Medical University of South Carolina, Charleston, SC (E.R.P., D.H.S.); the...
  • Cindy L. Grines
    From the Department of Cardiovascular Medicine, William Beaumont Hospital, Royal Oak, MI (J.A.G., S.R.D., C.L.G.); Pinnacle Health, Moffitt Heart and Vascular Group, Wormleysburg, PA (B.M.); Veterans Affairs North Texas Healthcare System and University of Texas Southwestern Medical Center at Dallas, Dallas, TX (E.B.); Scottsdale Heart Group, Scottsdale Healthcare Hospital, Scottsdale, AZ (D.G.R.); Heart and Vascular Center, Medical University of South Carolina, Charleston, SC (E.R.P., D.H.S.); the...
  • David G. Rizik
    From the Department of Cardiovascular Medicine, William Beaumont Hospital, Royal Oak, MI (J.A.G., S.R.D., C.L.G.); Pinnacle Health, Moffitt Heart and Vascular Group, Wormleysburg, PA (B.M.); Veterans Affairs North Texas Healthcare System and University of Texas Southwestern Medical Center at Dallas, Dallas, TX (E.B.); Scottsdale Heart Group, Scottsdale Healthcare Hospital, Scottsdale, AZ (D.G.R.); Heart and Vascular Center, Medical University of South Carolina, Charleston, SC (E.R.P., D.H.S.); the...
  • Eric R. Powers
    From the Department of Cardiovascular Medicine, William Beaumont Hospital, Royal Oak, MI (J.A.G., S.R.D., C.L.G.); Pinnacle Health, Moffitt Heart and Vascular Group, Wormleysburg, PA (B.M.); Veterans Affairs North Texas Healthcare System and University of Texas Southwestern Medical Center at Dallas, Dallas, TX (E.B.); Scottsdale Heart Group, Scottsdale Healthcare Hospital, Scottsdale, AZ (D.G.R.); Heart and Vascular Center, Medical University of South Carolina, Charleston, SC (E.R.P., D.H.S.); the...
  • Daniel H. Steinberg
    From the Department of Cardiovascular Medicine, William Beaumont Hospital, Royal Oak, MI (J.A.G., S.R.D., C.L.G.); Pinnacle Health, Moffitt Heart and Vascular Group, Wormleysburg, PA (B.M.); Veterans Affairs North Texas Healthcare System and University of Texas Southwestern Medical Center at Dallas, Dallas, TX (E.B.); Scottsdale Heart Group, Scottsdale Healthcare Hospital, Scottsdale, AZ (D.G.R.); Heart and Vascular Center, Medical University of South Carolina, Charleston, SC (E.R.P., D.H.S.); the...
  • Kendrick A. Shunk
    From the Department of Cardiovascular Medicine, William Beaumont Hospital, Royal Oak, MI (J.A.G., S.R.D., C.L.G.); Pinnacle Health, Moffitt Heart and Vascular Group, Wormleysburg, PA (B.M.); Veterans Affairs North Texas Healthcare System and University of Texas Southwestern Medical Center at Dallas, Dallas, TX (E.B.); Scottsdale Heart Group, Scottsdale Healthcare Hospital, Scottsdale, AZ (D.G.R.); Heart and Vascular Center, Medical University of South Carolina, Charleston, SC (E.R.P., D.H.S.); the...
  • Giora Weisz
    From the Department of Cardiovascular Medicine, William Beaumont Hospital, Royal Oak, MI (J.A.G., S.R.D., C.L.G.); Pinnacle Health, Moffitt Heart and Vascular Group, Wormleysburg, PA (B.M.); Veterans Affairs North Texas Healthcare System and University of Texas Southwestern Medical Center at Dallas, Dallas, TX (E.B.); Scottsdale Heart Group, Scottsdale Healthcare Hospital, Scottsdale, AZ (D.G.R.); Heart and Vascular Center, Medical University of South Carolina, Charleston, SC (E.R.P., D.H.S.); the...
  • Pedro R. Moreno
    From the Department of Cardiovascular Medicine, William Beaumont Hospital, Royal Oak, MI (J.A.G., S.R.D., C.L.G.); Pinnacle Health, Moffitt Heart and Vascular Group, Wormleysburg, PA (B.M.); Veterans Affairs North Texas Healthcare System and University of Texas Southwestern Medical Center at Dallas, Dallas, TX (E.B.); Scottsdale Heart Group, Scottsdale Healthcare Hospital, Scottsdale, AZ (D.G.R.); Heart and Vascular Center, Medical University of South Carolina, Charleston, SC (E.R.P., D.H.S.); the...
  • Annapoorna Kini
    From the Department of Cardiovascular Medicine, William Beaumont Hospital, Royal Oak, MI (J.A.G., S.R.D., C.L.G.); Pinnacle Health, Moffitt Heart and Vascular Group, Wormleysburg, PA (B.M.); Veterans Affairs North Texas Healthcare System and University of Texas Southwestern Medical Center at Dallas, Dallas, TX (E.B.); Scottsdale Heart Group, Scottsdale Healthcare Hospital, Scottsdale, AZ (D.G.R.); Heart and Vascular Center, Medical University of South Carolina, Charleston, SC (E.R.P., D.H.S.); the...
  • Samin K. Sharma
    From the Department of Cardiovascular Medicine, William Beaumont Hospital, Royal Oak, MI (J.A.G., S.R.D., C.L.G.); Pinnacle Health, Moffitt Heart and Vascular Group, Wormleysburg, PA (B.M.); Veterans Affairs North Texas Healthcare System and University of Texas Southwestern Medical Center at Dallas, Dallas, TX (E.B.); Scottsdale Heart Group, Scottsdale Healthcare Hospital, Scottsdale, AZ (D.G.R.); Heart and Vascular Center, Medical University of South Carolina, Charleston, SC (E.R.P., D.H.S.); the...
  • Michael J. Hendricks
    From the Department of Cardiovascular Medicine, William Beaumont Hospital, Royal Oak, MI (J.A.G., S.R.D., C.L.G.); Pinnacle Health, Moffitt Heart and Vascular Group, Wormleysburg, PA (B.M.); Veterans Affairs North Texas Healthcare System and University of Texas Southwestern Medical Center at Dallas, Dallas, TX (E.B.); Scottsdale Heart Group, Scottsdale Healthcare Hospital, Scottsdale, AZ (D.G.R.); Heart and Vascular Center, Medical University of South Carolina, Charleston, SC (E.R.P., D.H.S.); the...
  • Steve T. Sum
    From the Department of Cardiovascular Medicine, William Beaumont Hospital, Royal Oak, MI (J.A.G., S.R.D., C.L.G.); Pinnacle Health, Moffitt Heart and Vascular Group, Wormleysburg, PA (B.M.); Veterans Affairs North Texas Healthcare System and University of Texas Southwestern Medical Center at Dallas, Dallas, TX (E.B.); Scottsdale Heart Group, Scottsdale Healthcare Hospital, Scottsdale, AZ (D.G.R.); Heart and Vascular Center, Medical University of South Carolina, Charleston, SC (E.R.P., D.H.S.); the...
  • Sean P. Madden
    From the Department of Cardiovascular Medicine, William Beaumont Hospital, Royal Oak, MI (J.A.G., S.R.D., C.L.G.); Pinnacle Health, Moffitt Heart and Vascular Group, Wormleysburg, PA (B.M.); Veterans Affairs North Texas Healthcare System and University of Texas Southwestern Medical Center at Dallas, Dallas, TX (E.B.); Scottsdale Heart Group, Scottsdale Healthcare Hospital, Scottsdale, AZ (D.G.R.); Heart and Vascular Center, Medical University of South Carolina, Charleston, SC (E.R.P., D.H.S.); the...
  • James E. Muller
    From the Department of Cardiovascular Medicine, William Beaumont Hospital, Royal Oak, MI (J.A.G., S.R.D., C.L.G.); Pinnacle Health, Moffitt Heart and Vascular Group, Wormleysburg, PA (B.M.); Veterans Affairs North Texas Healthcare System and University of Texas Southwestern Medical Center at Dallas, Dallas, TX (E.B.); Scottsdale Heart Group, Scottsdale Healthcare Hospital, Scottsdale, AZ (D.G.R.); Heart and Vascular Center, Medical University of South Carolina, Charleston, SC (E.R.P., D.H.S.); the...
  • Gregg W. Stone
    From the Department of Cardiovascular Medicine, William Beaumont Hospital, Royal Oak, MI (J.A.G., S.R.D., C.L.G.); Pinnacle Health, Moffitt Heart and Vascular Group, Wormleysburg, PA (B.M.); Veterans Affairs North Texas Healthcare System and University of Texas Southwestern Medical Center at Dallas, Dallas, TX (E.B.); Scottsdale Heart Group, Scottsdale Healthcare Hospital, Scottsdale, AZ (D.G.R.); Heart and Vascular Center, Medical University of South Carolina, Charleston, SC (E.R.P., D.H.S.); the...
  • Morton J. Kern
    From the Department of Cardiovascular Medicine, William Beaumont Hospital, Royal Oak, MI (J.A.G., S.R.D., C.L.G.); Pinnacle Health, Moffitt Heart and Vascular Group, Wormleysburg, PA (B.M.); Veterans Affairs North Texas Healthcare System and University of Texas Southwestern Medical Center at Dallas, Dallas, TX (E.B.); Scottsdale Heart Group, Scottsdale Healthcare Hospital, Scottsdale, AZ (D.G.R.); Heart and Vascular Center, Medical University of South Carolina, Charleston, SC (E.R.P., D.H.S.); the...

書誌事項

公開日
2011-10
DOI
  • 10.1161/circinterventions.111.963264
公開者
Ovid Technologies (Wolters Kluwer Health)

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説明

<jats:sec> <jats:title>Background—</jats:title> <jats:p>Percutaneous coronary intervention (PCI) is associated with periprocedural myocardial infarction (MI) in 3% to 15% of cases (depending on the definition used). In many cases, these MIs result from distal embolization of lipid-core plaque (LCP) constituents. Prospective identification of LCP with catheter-based near-infrared spectroscopy (NIRS) may predict an increased risk of periprocedural MI and facilitate development of preventive measures.</jats:p> </jats:sec> <jats:sec> <jats:title>Methods and Results—</jats:title> <jats:p> The present study analyzed the relationship between the presence of a large LCP (detected by NIRS) and periprocedural MI. Patients with stable preprocedural cardiac biomarkers undergoing stenting were identified from the COLOR Registry, an ongoing prospective observational study of patients undergoing NIRS before PCI. The extent of LCP in the treatment zone was calculated as the maximal lipid-core burden index (LCBI) measured by NIRS for each of the 4-mm longitudinal segments in the treatment zone. A periprocedural MI was defined as new cardiac biomarker elevation above 3× upper limit of normal. A total of 62 patients undergoing stenting met eligibility criteria. A large LCP (defined as a maxLCBI <jats:sub>4 mm</jats:sub> ≥500) was present in 14 of 62 lesions (22.6%), and periprocedural MI was documented in 9 of 62 (14.5%) of cases. Periprocedural MI occurred in 7 of 14 patients (50%) with a maxLCBI <jats:sub>4 mm</jats:sub> ≥500, compared with 2 of 48 patients (4.2%) patients with a lower maxLCBI <jats:sub>4 mm</jats:sub> ( <jats:italic>P</jats:italic> =0.0002). </jats:p> </jats:sec> <jats:sec> <jats:title>Conclusions—</jats:title> <jats:p>NIRS provides rapid, automated detection of extensive LCPs that are associated with a high risk of periprocedural MI, presumably due to embolization of plaque contents during coronary intervention.</jats:p> </jats:sec>

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