Imidate as the Intact Directing Group for the Cobalt-Catalyzed C–H Allylation
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- Ryo Tanaka
- Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan
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- Iku Tanimoto
- Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan
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- Masahiro Kojima
- Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan
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- Tatsuhiko Yoshino
- Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan
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- Shigeki Matsunaga
- Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan
書誌事項
- 公開日
- 2019-08-26
- 資源種別
- journal article
- 権利情報
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- https://doi.org/10.15223/policy-029
- https://doi.org/10.15223/policy-037
- https://doi.org/10.15223/policy-045
- DOI
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- 10.1021/acs.joc.9b01972
- 公開者
- American Chemical Society (ACS)
この論文をさがす
説明
Cobalt-catalyzed C-H allylation reactions of NH-free benzimidates using vinylcyclopropanes or allyl carbonate are reported. The reactive and relatively unstable imidate groups remain intact during the C-H allylations to afford functionalized imidates without dealcoholizations. The thus obtained allylated imidate was subsequently converted into other heterocyclic structures through a following C-H functionalization reaction, demonstrating the synthetic utility of this method.
収録刊行物
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- The Journal of Organic Chemistry
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The Journal of Organic Chemistry 84 (20), 13203-13210, 2019-08-26
American Chemical Society (ACS)
