Adherence to treatment in allergic rhinitis using mobile technology. The <scp>MASK</scp> Study
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- Enrica Menditto
- CIRFF Center of Pharmacoeconomics University of Naples Federico II Naples Italy
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- Elisio Costa
- UCIBIO REQUIMTE Faculty of Pharmacy, and Competence Center on Active and Healthy Ageing of University of Porto (Porto4Ageing) University of Porto Porto Portugal
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- Luis Midão
- UCIBIO REQUIMTE Faculty of Pharmacy, and Competence Center on Active and Healthy Ageing of University of Porto (Porto4Ageing) University of Porto Porto Portugal
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- Sinthia Bosnic‐Anticevich
- Woolcock Institute of Medical Research University of Sydney Woolcock Emphysema Centre and Sydney Local Health District Glebe New South Wales Australia
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- Ettore Novellino
- University of Naples Federico II Naples Italy
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- Slawomir Bialek
- Department of Biochemistry and Clinical Chemistry Faculty of Pharmacy with the Division of Laboratory Medicine Warsaw Medical University Warsaw Poland
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- Vitalis Briedis
- Lithuanian University of Health Sciences Kaunas Lithuania
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- Alpana Mair
- DG for Health and Social Care Scottish Government Edinburgh UK
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- Rojin Rajabian‐Soderlund
- Department of Nephrology and Endocrinology Karolinska University Hospital Stockholm Sweden
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- Sylvie Arnavielhe
- KYomed INNOV Montpellier France
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- Anna Bedbrook
- MACVIA‐France Fondation partenariale FMC VIA‐LR Montpellier France
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- Wienczyslawa Czarlewski
- Medical Consulting Czarlewski Levallois France
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- Isabella Annesi‐Maesano
- Epidemiology of Allergic and Respiratory Diseases Department Institute Pierre Louis of Epidemiology and Public Health INSERM and Sorbonne Université Medical School Saint Antoine Paris France
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- Josep M. Anto
- ISGlobAL Centre for Research in Environmental Epidemiology (CREAL) Barcelona Spain
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- Philippe Devillier
- Laboratoire de Pharmacologie Respiratoire UPRES EA220 Hôpital Foch Suresnes France
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- Govert De Vries
- Peercode BV Geldermalsen The Netherlands
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- Thomas Keil
- Institute of Social Medicine, Epidemiology and Health Economics Charité ‐ Universitätsmedizin Berlin Berlin Germany
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- Aziz Sheikh
- The Usher Institute of Population Health Sciences and Informatics The University of Edinburgh Edinburgh UK
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- Valentina Orlando
- CIRFF Center of Pharmacoeconomics University of Naples Federico II Naples Italy
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- Désirée Larenas‐Linnemann
- Center of Excellence in Asthma and Allergy Médica Sur Clinical Foundation and Hospital México City Mexico
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- Lorenzo Cecchi
- SOS Allergology and Clinical Immunology USL Toscana Centro Prato Italy
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- Giulia De Feo
- Department of Medicine, Surgery and Dentistry “Scuola Medica Salernitana” University of Salerno Salerno Italy
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- M. Illario
- Division for Health Innovation Campania Region and Federico II University Hospital Naples (R&D and DISMET) Naples Italy
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- Cristiana Stellato
- Department of Medicine, Surgery and Dentistry “Scuola Medica Salernitana” University of Salerno Salerno Italy
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- Joao Fonseca
- CINTESIS Center for Research in Health Technologies and Information Systems Faculdade de Medicina da Universidade do Porto Porto Portugal
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- Joao Malva
- Faculty of Medicine Coimbra Institute for Clinical and Biomedical Research (iCBR) University of Coimbra Coimbra Portugal
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- Mario Morais‐Almeida
- Allergy Center CUF Descobertas Hospital Lisbon Portugal
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- Ana Maria Pereira
- Allergy Unit CUF‐Porto Hospital and Institute Porto Portugal
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- Ana Maria Todo‐Bom
- Imunoalergologia Centro Hospitalar Universitário de Coimbra and Faculty of Medicine University of Coimbra Coimbra Portugal
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- Violeta Kvedariene
- Faculty of Medicine Vilnius University Vilnius Lithuania
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- Arunas Valiulis
- Department of Public Health Clinic of Children's Diseases, and Institute of Health Sciences Vilnius University Institute of Clinical Medicine Vilnius Lithuania
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- Karl Christian Bergmann
- Charité – Universitätsmedizin Berlin Humboldt‐Universität zu Berlin Berlin Germany
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- Ludger Klimek
- Euforea Brussels Belgium
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- Ralph Mösges
- Medical Faculty Institute of Medical Statistics, and Computational Biology University of Cologne Cologne Germany
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- Oliver Pfaar
- Department of Otorhinolaryngology, Head and Neck Surgery Section of Rhinology and Allergy University Hospital Marburg Phillipps‐Universität Marburg Germany
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- Torsten Zuberbier
- Charité – Universitätsmedizin Berlin Humboldt‐Universität zu Berlin Berlin Germany
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- Vicky Cardona
- Allergy Section Department of Internal Medicine Hospital Vall d'Hebron, & ARADyAL Spanish Research Network Barcelona Spain
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- Joaquim Mullol
- Rhinology Unit & Smell Clinic ENT Department Hospital Clínic Barcelona Spain
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- Nikos G. Papadopoulos
- Division of Infection, Immunity& Respiratory Medicine Royal Manchester Children's Hospital University of Manchester Manchester UK
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- Emmanuel P. Prokopakis
- Department of Otorhinolaryngology University of Crete School of Medicine Heraklion Greece
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- Mike Bewick
- iQ4U Consultants Ltd London UK
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- Dermot Ryan
- Allergy and Respiratory Research Group The University of Edinburgh Edinburgh UK
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- Regina E. Roller‐Wirnsberger
- Department of Internal Medicine Medical University of Graz Graz Austria
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- Peter Valentin Tomazic
- Department of ENT Medical University of Graz Graz Austria
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- Alvaro A. Cruz
- ProAR – Nucleo de Excelencia em Asma Federal University of Bahia Salvador Brazil
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- Piotr Kuna
- Division of Internal Medicine, Asthma and Allergy Barlicki University Hospital Medical University of Lodz Lodz Poland
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- Boleslaw Samolinski
- Department of Prevention of Envinronmental Hazards and Allergology Medical University of Warsaw Warsaw Poland
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- Wytske J. Fokkens
- Department of Otorhinolaryngology Academic Medical Centre Amsterdam The Netherlands
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- Sietze Reitsma
- Department of Otorhinolaryngology Academic Medical Centre Amsterdam The Netherlands
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- Isabelle Bosse
- Allergist La Rochelle France
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- Jean‐François Fontaine
- Allergist Reims France
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- Daniel Laune
- KYomed INNOV Montpellier France
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- Tari Haahtela
- Skin and Allergy Hospital Helsinki University Hospital and University of Helsinki Helsinki Finland
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- Sanna Toppila‐Salmi
- Skin and Allergy Hospital Helsinki University Hospital and University of Helsinki Helsinki Finland
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- Claus Bachert
- Upper Airways Research Laboratory ENT Department Ghent University Hospital Ghent Belgium
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- Peter W. Hellings
- Department of Otorhinolaryngology Univ Hospitals Leuven Leuven Belgium
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- Erik Melén
- Sachs’ Children and Youth Hospital Södersjukhuset Stockholm Sweden
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- Magnus Wickman
- Centre for Clinical Research Sörmland Uppsala University Eskilstuna Sweden
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- Carsten Bindslev‐Jensen
- Department of Dermatology and Allergy Centre Odense University Hospital Odense Research Center for Anaphylaxis (ORCA) Odense Denmark
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- Esben Eller
- Department of Dermatology and Allergy Centre Odense University Hospital Odense Research Center for Anaphylaxis (ORCA) Odense Denmark
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- Robyn E. O'Hehir
- Department of Allergy, Immunology and Respiratory Medicine Alfred Hospital and Central Clinical School Monash University Melbourne Victoria Australia
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- Cemal Cingi
- ENT Department Medical Faculty Eskisehir Osmangazi University Eskisehir Turkey
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- Bilun Gemicioğlu
- Department of Pulmonary Diseases Cerrahpasa Faculty of Medicine Istanbul University Istanbul Turkey
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- Omer Kalayci
- Pediatric Allergy and Asthma Unit Hacettepe University School of Medicine Ankara Turkey
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- Juan Carlos Ivancevich
- Servicio de Alergia e Immunologia Clinica Santa Isabel Buenos Aires Argentina
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- Jean Bousquet
- MACVIA‐France Fondation partenariale FMC VIA‐LR Montpellier France
抄録
<jats:title>Summary</jats:title><jats:sec><jats:title>Background</jats:title><jats:p>Mobile technology may help to better understand the adherence to treatment. <jats:styled-content style="fixed-case">MASK</jats:styled-content>‐rhinitis (Mobile Airways Sentinel NetworK for allergic rhinitis) is a patient‐centred <jats:styled-content style="fixed-case">ICT</jats:styled-content> system. A mobile phone app (the <jats:italic>Allergy Diary)</jats:italic> central to <jats:styled-content style="fixed-case">MASK</jats:styled-content> is available in 22 countries.</jats:p></jats:sec><jats:sec><jats:title>Objectives</jats:title><jats:p>To assess the adherence to treatment in allergic rhinitis patients using the <jats:italic>Allergy Diary</jats:italic> App.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>An observational cross‐sectional study was carried out on all users who filled in the <jats:italic>Allergy Diary</jats:italic> from 1 January 2016 to 1 August 2017. Secondary adherence was assessed by using the modified Medication Possession Ratio (<jats:styled-content style="fixed-case">MPR</jats:styled-content>) and the Proportion of days covered (<jats:styled-content style="fixed-case">PDC</jats:styled-content>) approach.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>A total of 12 143 users were registered. A total of 6 949 users reported at least one <jats:styled-content style="fixed-case">VAS</jats:styled-content> data recording. Among them, 1 887 users reported ≥7 <jats:styled-content style="fixed-case">VAS</jats:styled-content> data. About 1 195 subjects were included in the analysis of adherence. One hundred and thirty‐six (11.28%) users were adherent (<jats:styled-content style="fixed-case">MPR</jats:styled-content> ≥70% and <jats:styled-content style="fixed-case">PDC</jats:styled-content> ≤1.25), 51 (4.23%) were partly adherent (<jats:styled-content style="fixed-case">MPR</jats:styled-content> ≥70% and <jats:styled-content style="fixed-case">PDC</jats:styled-content> = 1.50) and 176 (14.60%) were switchers. On the other hand, 832 (69.05%) users were non‐adherent to medications (<jats:styled-content style="fixed-case">MPR</jats:styled-content> <70%). Of those, the largest group was non‐adherent to medications and the time interval was increased in 442 (36.68%) users.</jats:p></jats:sec><jats:sec><jats:title>Conclusion and clinical relevance</jats:title><jats:p>Adherence to treatment is low. The relative efficacy of continuous vs on‐demand treatment for allergic rhinitis symptoms is still a matter of debate. This study shows an approach for measuring retrospective adherence based on a mobile app. This also represents a novel approach for analysing medication‐taking behaviour in a real‐world setting.</jats:p></jats:sec>
収録刊行物
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- Clinical & Experimental Allergy
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Clinical & Experimental Allergy 49 (4), 442-460, 2019-03-12
Wiley
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詳細情報 詳細情報について
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- CRID
- 1361975845329259776
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- ISSN
- 13652222
- 09547894
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- データソース種別
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- Crossref
- KAKEN