Commensal Host-Bacterial Relationships in the Gut

  • Lora V. Hooper
    Department of Molecular Biology and Pharmacology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Jeffrey I. Gordon
    Department of Molecular Biology and Pharmacology, Washington University School of Medicine, St. Louis, MO 63110, USA.

書誌事項

公開日
2001-05-11
DOI
  • 10.1126/science.1058709
公開者
American Association for the Advancement of Science (AAAS)

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説明

<jats:p>One potential outcome of the adaptive coevolution of humans and bacteria is the development of commensal relationships, where neither partner is harmed, or symbiotic relationships, where unique metabolic traits or other benefits are provided. Our gastrointestinal tract is colonized by a vast community of symbionts and commensals that have important effects on immune function, nutrient processing, and a broad range of other host activities. The current genomic revolution offers an unprecedented opportunity to identify the molecular foundations of these relationships so that we can understand how they contribute to our normal physiology and how they can be exploited to develop new therapeutic strategies.</jats:p>

収録刊行物

  • Science

    Science 292 (5519), 1115-1118, 2001-05-11

    American Association for the Advancement of Science (AAAS)

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