Detection of Chromosomal Alterations in the Circulation of Cancer Patients with Whole-Genome Sequencing
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- Rebecca J. Leary
- Ludwig Center for Cancer Genetics and Howard Hughes Medical Institutions, Johns Hopkins Kimmel Cancer Center, Baltimore, MD 21287, USA.
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- Mark Sausen
- Ludwig Center for Cancer Genetics and Howard Hughes Medical Institutions, Johns Hopkins Kimmel Cancer Center, Baltimore, MD 21287, USA.
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- Isaac Kinde
- Ludwig Center for Cancer Genetics and Howard Hughes Medical Institutions, Johns Hopkins Kimmel Cancer Center, Baltimore, MD 21287, USA.
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- Nickolas Papadopoulos
- Ludwig Center for Cancer Genetics and Howard Hughes Medical Institutions, Johns Hopkins Kimmel Cancer Center, Baltimore, MD 21287, USA.
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- John D. Carpten
- Translational Genomics Research Institute, Phoenix, AZ 85044, USA.
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- David Craig
- Translational Genomics Research Institute, Phoenix, AZ 85044, USA.
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- Joyce O’Shaughnessy
- Baylor Sammons Cancer Center, Texas Oncology, US Oncology, Dallas, TX 75246, USA.
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- Kenneth W. Kinzler
- Ludwig Center for Cancer Genetics and Howard Hughes Medical Institutions, Johns Hopkins Kimmel Cancer Center, Baltimore, MD 21287, USA.
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- Giovanni Parmigiani
- Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
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- Bert Vogelstein
- Ludwig Center for Cancer Genetics and Howard Hughes Medical Institutions, Johns Hopkins Kimmel Cancer Center, Baltimore, MD 21287, USA.
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- Luis A. Diaz
- Ludwig Center for Cancer Genetics and Howard Hughes Medical Institutions, Johns Hopkins Kimmel Cancer Center, Baltimore, MD 21287, USA.
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- Victor E. Velculescu
- Ludwig Center for Cancer Genetics and Howard Hughes Medical Institutions, Johns Hopkins Kimmel Cancer Center, Baltimore, MD 21287, USA.
書誌事項
- 公開日
- 2012-11-28
- DOI
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- 10.1126/scitranslmed.3004742
- 公開者
- American Association for the Advancement of Science (AAAS)
この論文をさがす
説明
<jats:p>Massively parallel sequencing directly detects tumor-derived chromosomal alterations in plasma DNA from cancer patients.</jats:p>
収録刊行物
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- Science Translational Medicine
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Science Translational Medicine 4 (162), 162ra154-, 2012-11-28
American Association for the Advancement of Science (AAAS)