The dietary compound luteolin inhibits pancreatic cancer growth by targeting BCL-2

  • Zhimei Li
    Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation
  • Yiyuan Zhang
    Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation
  • Lixia Chen
    Wuya College of Innovation
  • Hua Li
    Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation

Description

<p>Luteolin, a bioactive flavonoid from celery (<italic>Apium graveolens</italic>), has been rationally proved to trigger SW1990 cells to apoptosis by targeting BCL-2, and may serve as a potential agent for this cancer therapy.</p>

Journal

  • Food & Function

    Food & Function 9 (5), 3018-3027, 2018

    Royal Society of Chemistry (RSC)

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