Anti-mutagenic chalcones: Antagonizing the mutagenicity of benzo(a)pyrene on Salmonella typhimurium
書誌事項
- 公開日
- 1983-05
- 権利情報
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- https://www.elsevier.com/tdm/userlicense/1.0/
- DOI
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- 10.1016/0006-291x(83)91693-5
- 公開者
- Elsevier BV
この論文をさがす
説明
Several chalcone derivatives; e.g. Ro 09-0204, Ro 09-0323 and Ro 09-0501 were found to reduce markedly the revertant increase of Salmonella typhimurium TA100 by benzo(a)pyrene during the incubation with S-9 Mix. The antimutagenic activity was 100 - 700 times stronger than that of L-ascorbic acid. Effect on other mutagens, the structure activity relationship and the possible mechanism of action are briefly discussed.
収録刊行物
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- Biochemical and Biophysical Research Communications
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Biochemical and Biophysical Research Communications 112 (3), 833-842, 1983-05
Elsevier BV
