Growthcurver: an R package for obtaining interpretable metrics from microbial growth curves
説明
<jats:title>Abstract</jats:title><jats:sec> <jats:title>Background</jats:title> <jats:p>Plate readers can measure the growth curves of many microbial strains in a high-throughput fashion. The hundreds of absorbance readings collected simultaneously for hundreds of samples create technical hurdles for data analysis.</jats:p> </jats:sec><jats:sec> <jats:title>Results</jats:title> <jats:p>Growthcurver summarizes the growth characteristics of microbial growth curve experiments conducted in a plate reader. The data are fitted to a standard form of the logistic equation, and the parameters have clear interpretations on population-level characteristics, like doubling time, carrying capacity, and growth rate.</jats:p> </jats:sec><jats:sec> <jats:title>Conclusions</jats:title> <jats:p>Growthcurver is an easy-to-use R package available for installation from the Comprehensive R Archive Network (CRAN). The source code is available under the GNU General Public License and can be obtained from Github (Sprouffske K, Growthcurver sourcecode, 2016).</jats:p> </jats:sec>
収録刊行物
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- BMC Bioinformatics
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BMC Bioinformatics 17 (1), 172-, 2016-04-19
Springer Science and Business Media LLC
