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- Shinya Sato
- Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, USA
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- Alissa M. Weaver
- Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, USA
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- Philip Stahl
- editor
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- Graça Raposo
- editor
説明
<jats:p>Extracellular vesicles (EVs) are membrane vesicles that are released from cells and mediate cell–cell communication. EVs carry protein, lipid, and nucleic acid cargoes that interact with recipient cells to alter their phenotypes. Evidence is accumulating that tumor-derived EVs can play important roles in all steps of cancer progression. Here, we review recent studies reporting critical roles for EVs in four major areas of cancer progression: promotion of cancer invasiveness and motility, enhancement of angiogenesis and vessel permeability, conditioning premetastatic niches, and immune suppression.</jats:p>
収録刊行物
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- Essays in Biochemistry
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Essays in Biochemistry 62 (2), 149-163, 2018-04-17
Portland Press Ltd.
