A Randomized Study to Compare Ramp Versus Burst Antitachycardia Pacing Therapies to Treat Fast Ventricular Tachyarrhythmias in Patients With Implantable Cardioverter Defibrillators

DOI Web Site 被引用文献4件
  • Michele M. Gulizia
    From the Garibaldi-Nesima Hospital (M.M.G.), Catania; Civico e Benfratelli Hospital (L.P.), Palermo; Rummo Hospital (M.S.), Benevento; S. Antonio Abate Hospital (C.P.), Trapani; Umberto I Hospital (C.V.), Enna; Perrino Hospital (M.C.S.), Brindisi; S. Sebastiano Hospital (F.M.), Caserta; Villa Sofia Hospital (O.P.), Palermo; S. Elia Hospital (S.G.), Caltanisetta; Moscatello Hospital (G.C.), Augusta; S. Giovanni di Dio Hospital (I.V.), Agrigento; Garibaldi Hospital (S.M.), Catania; and Medtronic Italy...
  • Leandro Piraino
    From the Garibaldi-Nesima Hospital (M.M.G.), Catania; Civico e Benfratelli Hospital (L.P.), Palermo; Rummo Hospital (M.S.), Benevento; S. Antonio Abate Hospital (C.P.), Trapani; Umberto I Hospital (C.V.), Enna; Perrino Hospital (M.C.S.), Brindisi; S. Sebastiano Hospital (F.M.), Caserta; Villa Sofia Hospital (O.P.), Palermo; S. Elia Hospital (S.G.), Caltanisetta; Moscatello Hospital (G.C.), Augusta; S. Giovanni di Dio Hospital (I.V.), Agrigento; Garibaldi Hospital (S.M.), Catania; and Medtronic Italy...
  • Marino Scherillo
    From the Garibaldi-Nesima Hospital (M.M.G.), Catania; Civico e Benfratelli Hospital (L.P.), Palermo; Rummo Hospital (M.S.), Benevento; S. Antonio Abate Hospital (C.P.), Trapani; Umberto I Hospital (C.V.), Enna; Perrino Hospital (M.C.S.), Brindisi; S. Sebastiano Hospital (F.M.), Caserta; Villa Sofia Hospital (O.P.), Palermo; S. Elia Hospital (S.G.), Caltanisetta; Moscatello Hospital (G.C.), Augusta; S. Giovanni di Dio Hospital (I.V.), Agrigento; Garibaldi Hospital (S.M.), Catania; and Medtronic Italy...
  • Calogero Puntrello
    From the Garibaldi-Nesima Hospital (M.M.G.), Catania; Civico e Benfratelli Hospital (L.P.), Palermo; Rummo Hospital (M.S.), Benevento; S. Antonio Abate Hospital (C.P.), Trapani; Umberto I Hospital (C.V.), Enna; Perrino Hospital (M.C.S.), Brindisi; S. Sebastiano Hospital (F.M.), Caserta; Villa Sofia Hospital (O.P.), Palermo; S. Elia Hospital (S.G.), Caltanisetta; Moscatello Hospital (G.C.), Augusta; S. Giovanni di Dio Hospital (I.V.), Agrigento; Garibaldi Hospital (S.M.), Catania; and Medtronic Italy...
  • Calogero Vasco
    From the Garibaldi-Nesima Hospital (M.M.G.), Catania; Civico e Benfratelli Hospital (L.P.), Palermo; Rummo Hospital (M.S.), Benevento; S. Antonio Abate Hospital (C.P.), Trapani; Umberto I Hospital (C.V.), Enna; Perrino Hospital (M.C.S.), Brindisi; S. Sebastiano Hospital (F.M.), Caserta; Villa Sofia Hospital (O.P.), Palermo; S. Elia Hospital (S.G.), Caltanisetta; Moscatello Hospital (G.C.), Augusta; S. Giovanni di Dio Hospital (I.V.), Agrigento; Garibaldi Hospital (S.M.), Catania; and Medtronic Italy...
  • Maria Carmela Scianaro
    From the Garibaldi-Nesima Hospital (M.M.G.), Catania; Civico e Benfratelli Hospital (L.P.), Palermo; Rummo Hospital (M.S.), Benevento; S. Antonio Abate Hospital (C.P.), Trapani; Umberto I Hospital (C.V.), Enna; Perrino Hospital (M.C.S.), Brindisi; S. Sebastiano Hospital (F.M.), Caserta; Villa Sofia Hospital (O.P.), Palermo; S. Elia Hospital (S.G.), Caltanisetta; Moscatello Hospital (G.C.), Augusta; S. Giovanni di Dio Hospital (I.V.), Agrigento; Garibaldi Hospital (S.M.), Catania; and Medtronic Italy...
  • Franco Mascia
    From the Garibaldi-Nesima Hospital (M.M.G.), Catania; Civico e Benfratelli Hospital (L.P.), Palermo; Rummo Hospital (M.S.), Benevento; S. Antonio Abate Hospital (C.P.), Trapani; Umberto I Hospital (C.V.), Enna; Perrino Hospital (M.C.S.), Brindisi; S. Sebastiano Hospital (F.M.), Caserta; Villa Sofia Hospital (O.P.), Palermo; S. Elia Hospital (S.G.), Caltanisetta; Moscatello Hospital (G.C.), Augusta; S. Giovanni di Dio Hospital (I.V.), Agrigento; Garibaldi Hospital (S.M.), Catania; and Medtronic Italy...
  • Orazio Pensabene
    From the Garibaldi-Nesima Hospital (M.M.G.), Catania; Civico e Benfratelli Hospital (L.P.), Palermo; Rummo Hospital (M.S.), Benevento; S. Antonio Abate Hospital (C.P.), Trapani; Umberto I Hospital (C.V.), Enna; Perrino Hospital (M.C.S.), Brindisi; S. Sebastiano Hospital (F.M.), Caserta; Villa Sofia Hospital (O.P.), Palermo; S. Elia Hospital (S.G.), Caltanisetta; Moscatello Hospital (G.C.), Augusta; S. Giovanni di Dio Hospital (I.V.), Agrigento; Garibaldi Hospital (S.M.), Catania; and Medtronic Italy...
  • Salvatore Giglia
    From the Garibaldi-Nesima Hospital (M.M.G.), Catania; Civico e Benfratelli Hospital (L.P.), Palermo; Rummo Hospital (M.S.), Benevento; S. Antonio Abate Hospital (C.P.), Trapani; Umberto I Hospital (C.V.), Enna; Perrino Hospital (M.C.S.), Brindisi; S. Sebastiano Hospital (F.M.), Caserta; Villa Sofia Hospital (O.P.), Palermo; S. Elia Hospital (S.G.), Caltanisetta; Moscatello Hospital (G.C.), Augusta; S. Giovanni di Dio Hospital (I.V.), Agrigento; Garibaldi Hospital (S.M.), Catania; and Medtronic Italy...
  • Giacomo Chiarandà
    From the Garibaldi-Nesima Hospital (M.M.G.), Catania; Civico e Benfratelli Hospital (L.P.), Palermo; Rummo Hospital (M.S.), Benevento; S. Antonio Abate Hospital (C.P.), Trapani; Umberto I Hospital (C.V.), Enna; Perrino Hospital (M.C.S.), Brindisi; S. Sebastiano Hospital (F.M.), Caserta; Villa Sofia Hospital (O.P.), Palermo; S. Elia Hospital (S.G.), Caltanisetta; Moscatello Hospital (G.C.), Augusta; S. Giovanni di Dio Hospital (I.V.), Agrigento; Garibaldi Hospital (S.M.), Catania; and Medtronic Italy...
  • Ignazio Vaccaro
    From the Garibaldi-Nesima Hospital (M.M.G.), Catania; Civico e Benfratelli Hospital (L.P.), Palermo; Rummo Hospital (M.S.), Benevento; S. Antonio Abate Hospital (C.P.), Trapani; Umberto I Hospital (C.V.), Enna; Perrino Hospital (M.C.S.), Brindisi; S. Sebastiano Hospital (F.M.), Caserta; Villa Sofia Hospital (O.P.), Palermo; S. Elia Hospital (S.G.), Caltanisetta; Moscatello Hospital (G.C.), Augusta; S. Giovanni di Dio Hospital (I.V.), Agrigento; Garibaldi Hospital (S.M.), Catania; and Medtronic Italy...
  • Salvatore Mangiameli
    From the Garibaldi-Nesima Hospital (M.M.G.), Catania; Civico e Benfratelli Hospital (L.P.), Palermo; Rummo Hospital (M.S.), Benevento; S. Antonio Abate Hospital (C.P.), Trapani; Umberto I Hospital (C.V.), Enna; Perrino Hospital (M.C.S.), Brindisi; S. Sebastiano Hospital (F.M.), Caserta; Villa Sofia Hospital (O.P.), Palermo; S. Elia Hospital (S.G.), Caltanisetta; Moscatello Hospital (G.C.), Augusta; S. Giovanni di Dio Hospital (I.V.), Agrigento; Garibaldi Hospital (S.M.), Catania; and Medtronic Italy...
  • Dario Corrao
    From the Garibaldi-Nesima Hospital (M.M.G.), Catania; Civico e Benfratelli Hospital (L.P.), Palermo; Rummo Hospital (M.S.), Benevento; S. Antonio Abate Hospital (C.P.), Trapani; Umberto I Hospital (C.V.), Enna; Perrino Hospital (M.C.S.), Brindisi; S. Sebastiano Hospital (F.M.), Caserta; Villa Sofia Hospital (O.P.), Palermo; S. Elia Hospital (S.G.), Caltanisetta; Moscatello Hospital (G.C.), Augusta; S. Giovanni di Dio Hospital (I.V.), Agrigento; Garibaldi Hospital (S.M.), Catania; and Medtronic Italy...
  • Elisabetta Santi
    From the Garibaldi-Nesima Hospital (M.M.G.), Catania; Civico e Benfratelli Hospital (L.P.), Palermo; Rummo Hospital (M.S.), Benevento; S. Antonio Abate Hospital (C.P.), Trapani; Umberto I Hospital (C.V.), Enna; Perrino Hospital (M.C.S.), Brindisi; S. Sebastiano Hospital (F.M.), Caserta; Villa Sofia Hospital (O.P.), Palermo; S. Elia Hospital (S.G.), Caltanisetta; Moscatello Hospital (G.C.), Augusta; S. Giovanni di Dio Hospital (I.V.), Agrigento; Garibaldi Hospital (S.M.), Catania; and Medtronic Italy...
  • Andrea Grammatico
    From the Garibaldi-Nesima Hospital (M.M.G.), Catania; Civico e Benfratelli Hospital (L.P.), Palermo; Rummo Hospital (M.S.), Benevento; S. Antonio Abate Hospital (C.P.), Trapani; Umberto I Hospital (C.V.), Enna; Perrino Hospital (M.C.S.), Brindisi; S. Sebastiano Hospital (F.M.), Caserta; Villa Sofia Hospital (O.P.), Palermo; S. Elia Hospital (S.G.), Caltanisetta; Moscatello Hospital (G.C.), Augusta; S. Giovanni di Dio Hospital (I.V.), Agrigento; Garibaldi Hospital (S.M.), Catania; and Medtronic Italy...

書誌事項

タイトル別名
  • The PITAGORA ICD Trial

説明

<jats:p> <jats:bold> <jats:italic>Background—</jats:italic> </jats:bold> In patients with implantable cardioverter-defibrillators (ICDs), antitachycardia pacing (ATP) is highly effective in terminating fast ventricular tachycardias (FVTs) and lowers the use of high-energy shocks, without increasing the risk of arrhythmia acceleration or syncope. </jats:p> <jats:p> <jats:bold> <jats:italic>Methods and Results—</jats:italic> </jats:bold> The aim of the PITAGORA ICD trial was to randomly compare 2 ATP strategies (88% coupling interval burst versus 91% coupling interval ramp, both 8 pulses) in terms of ATP efficacy, arrhythmia acceleration, and syncope. Two hundred six ICD patients (83% male, 67�11 years) were enrolled. FVT episodes with cycle lengths between 240 and 320 ms were treated by 1 ATP sequence and, in the event of failure, by shocks. Over a median follow-up of 36 months, 829 spontaneous ventricular tachyarrhythmia episodes were detected in 79 patients. Episode review identified 595 episodes as true ventricular arrhythmias in 72 patients; devices classified 111 (18.7%) episodes as VF, 216 (36.3%) as FVT, and 268 (45.0%) as VT. Fifty-six patients had 214 treated FVT episodes—2 FVTs self-terminated before ATP release; 44 (79%) of these had at least 1 effective ATP intervention, and 34 (61%) were spared ICD shocks. Burst terminated 100 of 133 (75.2%) FVT episodes, whereas ramp terminated 44 of 81 (54.3%; <jats:italic>P</jats:italic> =0.015). Acceleration occurred in 9 of 214 (4.2%) FVT episodes treated: 6 episodes in 3 ramp patients and 3 episodes in 3 burst patients. Two patients—1 in each group—suffered 1 syncopal event associated to a nonterminated FVT episode. </jats:p> <jats:p> <jats:bold> <jats:italic>Conclusions—</jats:italic> </jats:bold> Burst is significantly more efficacious than ramp in terminating FVT episodes. As the first therapy for FVT episodes, ATP carries a low risk of acceleration or syncopal events. </jats:p>

収録刊行物

被引用文献 (4)*注記

もっと見る

詳細情報 詳細情報について

問題の指摘

ページトップへ