Superficial layers of the medial entorhinal cortex replay independently of the hippocampus

  • J. O’Neill
    Institute of Science and Technology Austria (IST Austria), Am Campus 1, A–3400 Klosterneuburg, Austria.
  • C.N. Boccara
    Institute of Science and Technology Austria (IST Austria), Am Campus 1, A–3400 Klosterneuburg, Austria.
  • F. Stella
    Institute of Science and Technology Austria (IST Austria), Am Campus 1, A–3400 Klosterneuburg, Austria.
  • P. Schoenenberger
    Institute of Science and Technology Austria (IST Austria), Am Campus 1, A–3400 Klosterneuburg, Austria.
  • J. Csicsvari
    Institute of Science and Technology Austria (IST Austria), Am Campus 1, A–3400 Klosterneuburg, Austria.

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<jats:title>Parallel computation in memory-making</jats:title> <jats:p> The hippocampus plays a central role in the encoding, consolidation, and recall of memories. Consolidation and recall are thought to be executed by the replay of previously acquired memory traces by hippocampal cell assemblies. The hippocampus is thus considered to be the initiator of memory redistribution processes. However, O'Neill <jats:italic>et al.</jats:italic> now report that the superficial layers of the medial entorhinal cortex show replay events that are independent of hippocampal activity (see the Perspective by Moser and Gardner). Computations in memory systems may thus be organized in a less hierarchical, more parallel way than previously thought. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6321" page="184" related-article-type="in-this-issue" vol="355" xlink:href="10.1126/science.aag2787">184</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6321" page="131" related-article-type="in-this-issue" vol="355" xlink:href="10.1126/science.aam5404">131</jats:related-article> </jats:p>

収録刊行物

  • Science

    Science 355 (6321), 184-188, 2017-01-13

    American Association for the Advancement of Science (AAAS)

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