Predictive Value of Admission Platelet Volume Indices for In-hospital Major Adverse Cardiovascular Events in Acute ST-Segment Elevation Myocardial Infarction
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- Turgay Celik
- Department of Cardiology, Gulhane Military Medical Academy, Ankara, Turkey
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- Mehmet G. Kaya
- Department of Cardiology, Erciyes University School of Medicine, Kayseri, Turkey
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- Mahmut Akpek
- Department of Cardiology, Erciyes University School of Medicine, Kayseri, Turkey
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- Ozgur Gunebakmaz
- Department of Cardiology, Erciyes University School of Medicine, Kayseri, Turkey
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- Sevket Balta
- Department of Cardiology, Gulhane Military Medical Academy, Ankara, Turkey
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- Bahadir Sarli
- Department of Cardiology, Erciyes University School of Medicine, Kayseri, Turkey
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- Mustafa Duran
- Department of Cardiology, Erciyes University School of Medicine, Kayseri, Turkey
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- Sait Demirkol
- Department of Cardiology, Gulhane Military Medical Academy, Ankara, Turkey
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- Onur Kadir Uysal
- Department of Cardiology, Erciyes University School of Medicine, Kayseri, Turkey
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- Abdurrahman Oguzhan
- Department of Cardiology, Erciyes University School of Medicine, Kayseri, Turkey
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- C. Michael Gibson
- Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
説明
<jats:p> Although mean platelet volume (MPV) is an independent correlate of impaired angiographic reperfusion and 6-month mortality in ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (pPCI), there is less data regarding the association between platelet distribution width (PDW) and in-hospital major adverse cardiovascular events (MACEs). A total of 306 patients with STEMI pPCI were evaluated. No reflow was defined as a post-PCI thrombolysis in myocardial infarction (TIMI) flow grade of 0, 1, or 2 (group 1). Angiographic success was defined as TIMI flow grade 3 (group 2). The values of MPV and PDW were higher among patients with no reflow. In-stent thrombosis, nonfatal myocardial infarction, in-hospital mortality, and MACEs were significantly more frequent among patients with no reflow. In multivariate analysis, PDW, MPV, high-sensitivity C-reactive protein, and glucose on admission were independent correlates of in-hospital MACEs. Admission PDW and MPV are independent correlates of no reflow and in-hospital MACEs among patients with STEMI undergoing pPCI. </jats:p>
収録刊行物
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- Angiology
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Angiology 66 (2), 155-162, 2013-12-03
SAGE Publications
