Microbiome in healthy skin, update for dermatologists

  • B. Dréno
    Department of Dermato‐cancerology Nantes University Nantes France
  • E. Araviiskaia
    Department of Dermatology First Pavlov State Medical University of St. Petersburg St. Petersburg Russia
  • E. Berardesca
    San Gallicano Dermatological Institute Rome Italy
  • G. Gontijo
    Universidade Federal de Minas Gerais Belo Horizonte MG Brazil
  • M. Sanchez Viera
    Institute for Dermatology, Skin Health, Aging and Cancer Madrid Spain
  • L.F. Xiang
    Department of Dermatology Huashan Hospital Fudan University Shanghai China
  • R. Martin
    L'Oréal Research and Innovation Tours France
  • T. Bieber
    Department of Dermatology and Allergy University Medical Center Bonn Germany

書誌事項

公開日
2016-10-13
権利情報
  • http://creativecommons.org/licenses/by-nc/4.0/
DOI
  • 10.1111/jdv.13965
公開者
Wiley

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説明

<jats:title>Abstract</jats:title><jats:p>The skin is a complex barrier organ made of a symbiotic relationship between microbial communities and host tissue via complex signals provided by the innate and the adaptive immune systems. It is constantly exposed to various endogenous and exogenous factors which impact this balanced system potentially leading to inflammatory skin conditions comprising infections, allergies or autoimmune diseases. Unlike the gut and stool microbiome which has been studied and described for many years, investigations on the skin or scalp microbiome only started recently. Researchers in microbiology and dermatology started using modern methods such as pyrosequencing assays of bacterial 16S <jats:styled-content style="fixed-case">rRNA</jats:styled-content> genes to identify and characterize the different microorganisms present on the skin, to evaluate the bacterial diversity and their relative abundance and to understand how microbial diversity may contribute to skin health and dermatological conditions. This article aims to provide an overview on the knowledge about the skin microbiota, the microbiome and their importance in dermatology.</jats:p>

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