A review of polyvinyl alcohol and its uses in cartilage and orthopedic applications
書誌事項
- 公開日
- 2012-04-19
- 権利情報
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- http://onlinelibrary.wiley.com/termsAndConditions#vor
- DOI
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- 10.1002/jbm.b.32694
- 公開者
- Wiley
この論文をさがす
説明
<jats:title>Abstract</jats:title><jats:p>Polyvinyl alcohol (PVA) is a synthetic polymer derived from polyvinyl acetate through partial or full hydroxylation. PVA is commonly used in medical devices due to its low protein adsorption characteristics, biocompatibility, high water solubility, and chemical resistance. Some of the most common medical uses of PVA are in soft contact lenses, eye drops, embolization particles, tissue adhesion barriers, and as artificial cartilage and meniscus. The purpose of this review is to evaluate the available published information on PVA with respect to its safety as a medical device implant material for cartilage replacement. The review includes historical clinical use of PVA in orthopedics, and <jats:italic>in vitro</jats:italic> and <jats:italic>in vivo</jats:italic> biocompatibility studies. Finally, the safety recommendation involving the further development of PVA cryogels for cartilage replacement is addressed. © 2012 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater 2012.</jats:p>
収録刊行物
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- Journal of Biomedical Materials Research Part B: Applied Biomaterials
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Journal of Biomedical Materials Research Part B: Applied Biomaterials 100B (5), 1451-1457, 2012-04-19
Wiley
