The Biology of Oxygen Radicals

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  • The superoxide radical is an agent of oxygen toxicity; superoxide dismutases provide an important defense.

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<jats:p> The reactive superoxide radical, O <jats:sub>2</jats:sub> <jats:sup>-</jats:sup> , formerly of concern only to radiation chemists and radiobiologists, is now understood to be a normal product of the biological reduction of molecular oxygen. An unusual family of enzymes, the superoxide dismutases, protect against the deleterious actions of this radical by catalyzing its dismutation to hydrogen peroxide plus oxygen. </jats:p>

Journal

  • Science

    Science 201 (4359), 875-880, 1978-09-08

    American Association for the Advancement of Science (AAAS)

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