<i>AXR2</i> Encodes a Member of the Aux/IAA Protein Family

  • Punita Nagpal
    Department of Biology, University of North Carolina at Chapel Hill, CB #3280, Coker Hall, Chapel Hill, North Carolina 27599–3280 (P.N., A.S., J.W.R.);
  • Loni M. Walker
    Department of Biology, Indiana University, Bloomington, Indiana 47405 (L.M.W., C.T., M.E.); and
  • Jeff C. Young
    Department of Biology, Western Washington University, MS–9160, Bellingham, Washington 98225 (J.C.Y.)
  • Ami Sonawala
    Department of Biology, University of North Carolina at Chapel Hill, CB #3280, Coker Hall, Chapel Hill, North Carolina 27599–3280 (P.N., A.S., J.W.R.);
  • Candace Timpte
    Department of Biology, Indiana University, Bloomington, Indiana 47405 (L.M.W., C.T., M.E.); and
  • Mark Estelle
    Department of Biology, Indiana University, Bloomington, Indiana 47405 (L.M.W., C.T., M.E.); and
  • Jason W. Reed
    Department of Biology, University of North Carolina at Chapel Hill, CB #3280, Coker Hall, Chapel Hill, North Carolina 27599–3280 (P.N., A.S., J.W.R.);

書誌事項

公開日
2000-06-01
権利情報
  • https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model
DOI
  • 10.1104/pp.123.2.563
公開者
Oxford University Press (OUP)

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説明

<jats:title>Abstract</jats:title> <jats:p>The dominant gain-of-function axr2-1 mutation of Arabidopsis causes agravitropic root and shoot growth, a short hypocotyl and stem, and auxin-resistant root growth. We have cloned theAXR2 gene using a map-based approach, and find that it is the same as IAA7, a member of the IAA(indole-3-acetic acid) family of auxin-inducible genes. Theaxr2-1 mutation changes a single amino acid in conserved domain II of AXR2/IAA7. We isolated loss-of-function mutations inAXR2/IAA7 as intragenic suppressors ofaxr2-1 or in a screen for insertion mutations inIAA genes. A null mutant has a slightly longer hypocotyl than wild-type plants, indicating that AXR2/IAA7 controls development in light-grown seedlings, perhaps in concert with other gene products. Dark-grown axr2-1 mutant plants have short hypocotyls and make leaves, suggesting that activation of AXR2/IAA7 is sufficient to induce morphological responses normally elicited by light. Previously described semidominant mutations in two other Arabidopsis IAA genes cause some of the same phenotypes as axr2-1, but also cause distinct phenotypes. These results illustrate functional differences among members of the Arabidopsis IAA gene family.</jats:p>

収録刊行物

  • Plant Physiology

    Plant Physiology 123 (2), 563-574, 2000-06-01

    Oxford University Press (OUP)

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