NON‐SHIVERING THERMOGENESIS AND ITS THERMOREGULATORY SIGNIFICANCE

DOI Web Site Web Site 被引用文献2件

書誌事項

公開日
1973-02
権利情報
  • http://onlinelibrary.wiley.com/termsAndConditions#vor
DOI
  • 10.1111/j.1469-185x.1973.tb01115.x
公開者
Wiley

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説明

<jats:title>Summary</jats:title><jats:p>1. Non‐shivering thermogenesis (NST) is a heat‐production mechanism participating in the chemical thermoregulation of mammals.</jats:p><jats:p>2. NST is additional to shivering and takes place at temperatures close to the thermoneutral zone.</jats:p><jats:p>3. NST occurs in newborn mammals and in those that hibernate. In some adult mammals it can be induced by adaptation to cold.</jats:p><jats:p>4. In small mammals NST produces approximately the same amount of heat as shivering. It becomes less important with increasing body weight of the animals.</jats:p><jats:p>5. NST is regulated by the hypothalamus and it is based predominantly on the calorigenic action of noradrenaline released from sympathetic nerve‐endings.</jats:p><jats:p>Participation of other calorigenic substances and of the specific dynamic action of food cannot be excluded.</jats:p><jats:p>6. NST is localized mainly in skeletal muscles and in brown adipose tissue. Small amounts of NST may come from liver, intestine, heart and brain.</jats:p><jats:p>7. The biochemical basis of the calorigenic action of noradrenaline has not yet been fully elucidated.</jats:p>

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