PD-1: an inhibitory immunoreceptor involved in peripheral tolerance
書誌事項
- 公開日
- 2001-05
- 権利情報
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- https://www.elsevier.com/tdm/userlicense/1.0/
- DOI
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- 10.1016/s1471-4906(01)01888-9
- 公開者
- Elsevier BV
この論文をさがす
説明
PD-1 deficiency causes a variety of autoimmune diseases. Inhibitory signaling through the PD-1 receptor might therefore be involved in the regulation of peripheral tolerance. The constitutive expression of PD-1 ligands (PD-L1 and PD-L2) on parenchymal cells of heart, lung and kidney suggests that the PD-1-PD-L system could provide unique negative signaling to help prevent autoimmune diseases.
収録刊行物
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- Trends in Immunology
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Trends in Immunology 22 (5), 265-268, 2001-05
Elsevier BV