書誌事項
- 公開日
- 2017-02
- 権利情報
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- https://www.cambridge.org/core/terms
- DOI
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- 10.1192/bjp.bp.115.180752
- 公開者
- Royal College of Psychiatrists
この論文をさがす
説明
<jats:sec><jats:title>Background</jats:title><jats:p>Childhood maltreatment has been discussed as a risk factor for the development and maintenance of depression.</jats:p></jats:sec><jats:sec><jats:title>Aims</jats:title><jats:p>To examine the relationship between childhood maltreatment and adult depression with regard to depression incidence, severity, age at onset, course of illness and treatment response.</jats:p></jats:sec><jats:sec><jats:title>Method</jats:title><jats:p>We conducted meta-analyses of original articles reporting an association between childhood maltreatment and depression outcomes in adult populations.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>In total, 184 studies met inclusion criteria. Nearly half of patients with depression reported a history of childhood maltreatment. Maltreated individuals were 2.66 (95% CI 2.38–2.98) to 3.73 (95% CI 2.88–4.83) times more likely to develop depression in adulthood, had an earlier depression onset and were twice as likely to develop chronic or treatment-resistant depression. Depression severity was most prominently linked to childhood emotional maltreatment.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>Childhood maltreatment, especially emotional abuse and neglect, represents a risk factor for severe, early-onset, treatment-resistant depression with a chronic course.</jats:p></jats:sec>
収録刊行物
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- British Journal of Psychiatry
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British Journal of Psychiatry 210 (2), 96-104, 2017-02
Royal College of Psychiatrists
