Quantitative Metabolome Analysis Using Capillary Electrophoresis Mass Spectrometry

DOI Web Site PubMed PubMed 研究データあり 被引用文献265件 参考文献20件
  • Tomoyoshi Soga
    Institute for Advanced Biosciences, Keio University, Tsuruoka, Yamagata 997-0017, Japan, and Graduate School of Agricultural Sciences, Kyoto University, Kyoto 606-8502, Japan
  • Yoshiaki Ohashi
    Institute for Advanced Biosciences, Keio University, Tsuruoka, Yamagata 997-0017, Japan, and Graduate School of Agricultural Sciences, Kyoto University, Kyoto 606-8502, Japan
  • Yuki Ueno
    Institute for Advanced Biosciences, Keio University, Tsuruoka, Yamagata 997-0017, Japan, and Graduate School of Agricultural Sciences, Kyoto University, Kyoto 606-8502, Japan
  • Hisako Naraoka
    Institute for Advanced Biosciences, Keio University, Tsuruoka, Yamagata 997-0017, Japan, and Graduate School of Agricultural Sciences, Kyoto University, Kyoto 606-8502, Japan
  • Masaru Tomita
    Institute for Advanced Biosciences, Keio University, Tsuruoka, Yamagata 997-0017, Japan, and Graduate School of Agricultural Sciences, Kyoto University, Kyoto 606-8502, Japan
  • Takaaki Nishioka
    Institute for Advanced Biosciences, Keio University, Tsuruoka, Yamagata 997-0017, Japan, and Graduate School of Agricultural Sciences, Kyoto University, Kyoto 606-8502, Japan

書誌事項

公開日
2003-06-28
資源種別
journal article
DOI
  • 10.1021/pr034020m
公開者
American Chemical Society (ACS)

この論文をさがす

説明

A new approach for the comprehensive and quantitative analysis of charged metabolites by capillary electrophoresis mass spectrometry (CE-MS) is proposed. Metabolites are first separated by CE based on charge and size and then selectively detected using MS by monitoring over a large range of m/z values. This method enabled the determination of 352 metabolic standards and its utility was demonstrated in the analysis of 1692 metabolites from Bacillus subtilis extracts, revealing significant changes in metabolites during B. subtilis sporulation.

収録刊行物

被引用文献 (265)*注記

もっと見る

参考文献 (20)*注記

もっと見る

関連研究データ

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ