Mammalian Neural Stem Cells

DOI Web Site 被引用文献225件
  • Fred H. Gage
    The Salk Institute, Laboratory of Genetics, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.

書誌事項

公開日
2000-02-25
DOI
  • 10.1126/science.287.5457.1433
公開者
American Association for the Advancement of Science (AAAS)

この論文をさがす

説明

<jats:p>Neural stem cells exist not only in the developing mammalian nervous system but also in the adult nervous system of all mammalian organisms, including humans. Neural stem cells can also be derived from more primitive embryonic stem cells. The location of the adult stem cells and the brain regions to which their progeny migrate in order to differentiate remain unresolved, although the number of viable locations is limited in the adult. The mechanisms that regulate endogenous stem cells are poorly understood. Potential uses of stem cells in repair include transplantation to repair missing cells and the activation of endogenous cells to provide “self-repair.” Before the full potential of neural stem cells can be realized, we need to learn what controls their proliferation, as well as the various pathways of differentiation available to their daughter cells.</jats:p>

収録刊行物

  • Science

    Science 287 (5457), 1433-1438, 2000-02-25

    American Association for the Advancement of Science (AAAS)

被引用文献 (225)*注記

もっと見る

詳細情報 詳細情報について

問題の指摘

ページトップへ