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- Sandhya Shrivastava
- Department of Oral Pathology and Microbiology, Hi-Tech Dental College and Research Institute, Bhubneshwar, Odisha, India
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- Rupali Naik
- Dental Surgeon, Rural Hospital, Devrukh, Ratnagiri, Maharashtra, India
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- Hema Suryawanshi
- Department of Oral Pathology and Microbiology, Chhattisgarh Dental College and Research Institute, Rajnandgaon, Chhattisgarh, India
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- Neha Gupta
- Research Scientist and Consultant Stemgenn Therapeutics, New Delhi, India
書誌事項
- 公開日
- 2019-05
- DOI
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- 10.4103/jomfp.jomfp_85_17
- 公開者
- Ovid Technologies (Wolters Kluwer Health)
この論文をさがす
説明
<jats:p>Microchimerism is the presence of cells from one individual in another genetically distinct individual. Pregnancy is the main cause of natural microchimerism through transplacental bi-directional cell trafficking between mother and fetus. In addition to a variety of cell-free substances, it is now well-recognized that some cells are also exchanged in pregnancy. Furthermore, it is now known that microchimerism persists decades later both in mother and in her progeny. The consequences of pregnancy-related microchimerism are under active investigation. However, many authors have suggested a close relationship linking fetal microchimerism and the development of autoimmune diseases. Fetal microchimerism is emerging as a potential contributing factor in certain diseases, including cancer. Parallel studies in animal and human pregnancy suggest that microchimeric fetal cells play a role in wound healing. Role of these microchimeric cells in human health and disease is discussed here.</jats:p>
収録刊行物
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- Journal of Oral and Maxillofacial Pathology
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Journal of Oral and Maxillofacial Pathology 23 (2), 311-311, 2019-05
Ovid Technologies (Wolters Kluwer Health)
