Latest Advances in Cryogel Technology for Biomedical Applications

  • Adnan Memic
    Center of Nanotechnology King Abdulaziz University Jeddah 21589 Saudi Arabia
  • Thibault Colombani
    Department of Chemical Engineering Northeastern University Boston MA 02115 USA
  • Loek J. Eggermont
    Department of Chemical Engineering Northeastern University Boston MA 02115 USA
  • Mahboobeh Rezaeeyazdi
    Department of Chemical Engineering Northeastern University Boston MA 02115 USA
  • Joseph Steingold
    Department of Pharmaceutical Sciences Northeastern University Boston MA 02115 USA
  • Zach J. Rogers
    Department of Chemical Engineering Northeastern University Boston MA 02115 USA
  • Kasturi Joshi Navare
    Department of Chemical Engineering Northeastern University Boston MA 02115 USA
  • Halimatu S. Mohammed
    Department of Chemical Engineering Northeastern University Boston MA 02115 USA
  • Sidi A. Bencherif
    Department of Chemical Engineering Northeastern University Boston MA 02115 USA

書誌事項

公開日
2019-02-10
権利情報
  • http://onlinelibrary.wiley.com/termsAndConditions#vor
DOI
  • 10.1002/adtp.201800114
公開者
Wiley

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説明

<jats:title>Abstract</jats:title><jats:p>There exists a technological need for advanced materials with improved properties for emerging biomedical applications. Recent developments in macroporous materials have demonstrated their applicability as indispensable tools in biomedical research. Cryogels, which are materials with a macroporous 3D structure, are produced as a result of controlled freezing during polymerization with a highly interconnected polymer network. Cryogels’ interest lies in their ability to address some of the limitations of their hydrogel analogues. In this review, hydrogel and cryogel basic concepts are discussed as a short primer for readers unfamiliar with the cryogels literature. Next, a general overview of the methods for synthesis and characterization of cryogels is provided, highlighting key concepts relevant to cryogels and explaining their unique properties. Finally an in‐depth overview of specific technologies and fields where cryogels have been applied is given. It is argued that the latest advances in cryogel technologies are able to address challenges in bioseparation, tissue engineering, and other emerging bioengineering disciplines.</jats:p>

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