Glucosinolate Metabolites Required for an <i>Arabidopsis</i> Innate Immune Response

DOI Web Site 被引用文献45件
  • Nicole K. Clay
    Department of Genetics, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02114, USA.
  • Adewale M. Adio
    Department of Genetics, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02114, USA.
  • Carine Denoux
    Department of Genetics, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02114, USA.
  • Georg Jander
    Department of Genetics, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02114, USA.
  • Frederick M. Ausubel
    Department of Genetics, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02114, USA.

書誌事項

公開日
2009-01-02
DOI
  • 10.1126/science.1164627
公開者
American Association for the Advancement of Science (AAAS)

この論文をさがす

説明

<jats:p> The perception of pathogen or microbe-associated molecular pattern molecules by plants triggers a basal defense response analogous to animal innate immunity and is defined partly by the deposition of the glucan polymer callose at the cell wall at the site of pathogen contact. Transcriptional and metabolic profiling in <jats:italic>Arabidopsis</jats:italic> mutants, coupled with the monitoring of pathogen-triggered callose deposition, have identified major roles in pathogen response for the plant hormone ethylene and the secondary metabolite 4-methoxy-indol-3-ylmethylglucosinolate. Two genes, <jats:italic>PEN2</jats:italic> and <jats:italic>PEN3</jats:italic> , are also necessary for resistance to pathogens and are required for both callose deposition and glucosinolate activation, suggesting that the pathogen-triggered callose response is required for resistance to microbial pathogens. Our study shows that well-studied plant metabolites, previously identified as important in avoiding damage by herbivores, are also required as a component of the plant defense response against microbial pathogens. </jats:p>

収録刊行物

  • Science

    Science 323 (5910), 95-101, 2009-01-02

    American Association for the Advancement of Science (AAAS)

被引用文献 (45)*注記

もっと見る

詳細情報 詳細情報について

問題の指摘

ページトップへ