Pharmacological Profile of Xanthohumol, a Prenylated Flavonoid from Hops (Humulus lupulus)
-
- Ming Liu
- Key Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China
-
- Poul Hansen
- Department of Science, Systems and Models, Roskilde University, P.O. Box 260, DK-4000 Roskilde, Denmark
-
- Genzhu Wang
- Key Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China
-
- Lin Qiu
- Institute for Nutritional Sciences, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
-
- Jianjun Dong
- State Key Laboratory of Biological Fermentation Engineering of Beer, Qingdao 266061, China
-
- Hua Yin
- State Key Laboratory of Biological Fermentation Engineering of Beer, Qingdao 266061, China
-
- Zhonghua Qian
- State Key Laboratory of Biological Fermentation Engineering of Beer, Qingdao 266061, China
-
- Mei Yang
- State Key Laboratory of Biological Fermentation Engineering of Beer, Qingdao 266061, China
-
- Jinlai Miao
- State Key Laboratory of Biological Fermentation Engineering of Beer, Qingdao 266061, China
書誌事項
- 公開日
- 2015-01-07
- 権利情報
-
- https://creativecommons.org/licenses/by/4.0/
- DOI
-
- 10.3390/molecules20010754
- 公開者
- MDPI AG
説明
<jats:p>The female inflorescences of hops (Humulus lupulus L.), a well-known bittering agent used in the brewing industry, have long been used in traditional medicines. Xanthohumol (XN) is one of the bioactive substances contributing to its medical applications. Among foodstuffs XN is found primarily in beer and its natural occurrence is surveyed. In recent years, XN has received much attention for its biological effects. The present review describes the pharmacological aspects of XN and summarizes the most interesting findings obtained in the preclinical research related to this compound, including the pharmacological activity, the pharmacokinetics, and the safety of XN. Furthermore, the potential use of XN as a food additive considering its many positive biological effects is discussed.</jats:p>
収録刊行物
-
- Molecules
-
Molecules 20 (1), 754-779, 2015-01-07
MDPI AG