Weather-Related Changes in 24-Hour Blood Pressure Profile

  • Pietro Amedeo Modesti
    From the Clinica Medica Generale e Cardiologia (P.A.M., I.B., G.P., C.L., G.F.G.) and Interdepartmental Centre of Bioclimatology (P.A.M., M.M., S.O., G.M., G.F.G.), University of Florence, Florence; Institute of Biometeorology (M.M., L.M., G.M.), National Research Council, Florence; and Department of Clinical Medicine, Prevention, and Applied Biotechnologies (A.G., G.B., G.C., L.L., G.M., G.P.), University of Milano-Bicocca and Istituto Auxologico Italiano, Milan, Italy.
  • Marco Morabito
    From the Clinica Medica Generale e Cardiologia (P.A.M., I.B., G.P., C.L., G.F.G.) and Interdepartmental Centre of Bioclimatology (P.A.M., M.M., S.O., G.M., G.F.G.), University of Florence, Florence; Institute of Biometeorology (M.M., L.M., G.M.), National Research Council, Florence; and Department of Clinical Medicine, Prevention, and Applied Biotechnologies (A.G., G.B., G.C., L.L., G.M., G.P.), University of Milano-Bicocca and Istituto Auxologico Italiano, Milan, Italy.
  • Iacopo Bertolozzi
    From the Clinica Medica Generale e Cardiologia (P.A.M., I.B., G.P., C.L., G.F.G.) and Interdepartmental Centre of Bioclimatology (P.A.M., M.M., S.O., G.M., G.F.G.), University of Florence, Florence; Institute of Biometeorology (M.M., L.M., G.M.), National Research Council, Florence; and Department of Clinical Medicine, Prevention, and Applied Biotechnologies (A.G., G.B., G.C., L.L., G.M., G.P.), University of Milano-Bicocca and Istituto Auxologico Italiano, Milan, Italy.
  • Luciano Massetti
    From the Clinica Medica Generale e Cardiologia (P.A.M., I.B., G.P., C.L., G.F.G.) and Interdepartmental Centre of Bioclimatology (P.A.M., M.M., S.O., G.M., G.F.G.), University of Florence, Florence; Institute of Biometeorology (M.M., L.M., G.M.), National Research Council, Florence; and Department of Clinical Medicine, Prevention, and Applied Biotechnologies (A.G., G.B., G.C., L.L., G.M., G.P.), University of Milano-Bicocca and Istituto Auxologico Italiano, Milan, Italy.
  • Gabriele Panci
    From the Clinica Medica Generale e Cardiologia (P.A.M., I.B., G.P., C.L., G.F.G.) and Interdepartmental Centre of Bioclimatology (P.A.M., M.M., S.O., G.M., G.F.G.), University of Florence, Florence; Institute of Biometeorology (M.M., L.M., G.M.), National Research Council, Florence; and Department of Clinical Medicine, Prevention, and Applied Biotechnologies (A.G., G.B., G.C., L.L., G.M., G.P.), University of Milano-Bicocca and Istituto Auxologico Italiano, Milan, Italy.
  • Camilla Lumachi
    From the Clinica Medica Generale e Cardiologia (P.A.M., I.B., G.P., C.L., G.F.G.) and Interdepartmental Centre of Bioclimatology (P.A.M., M.M., S.O., G.M., G.F.G.), University of Florence, Florence; Institute of Biometeorology (M.M., L.M., G.M.), National Research Council, Florence; and Department of Clinical Medicine, Prevention, and Applied Biotechnologies (A.G., G.B., G.C., L.L., G.M., G.P.), University of Milano-Bicocca and Istituto Auxologico Italiano, Milan, Italy.
  • Alessia Giglio
    From the Clinica Medica Generale e Cardiologia (P.A.M., I.B., G.P., C.L., G.F.G.) and Interdepartmental Centre of Bioclimatology (P.A.M., M.M., S.O., G.M., G.F.G.), University of Florence, Florence; Institute of Biometeorology (M.M., L.M., G.M.), National Research Council, Florence; and Department of Clinical Medicine, Prevention, and Applied Biotechnologies (A.G., G.B., G.C., L.L., G.M., G.P.), University of Milano-Bicocca and Istituto Auxologico Italiano, Milan, Italy.
  • Grzegorz Bilo
    From the Clinica Medica Generale e Cardiologia (P.A.M., I.B., G.P., C.L., G.F.G.) and Interdepartmental Centre of Bioclimatology (P.A.M., M.M., S.O., G.M., G.F.G.), University of Florence, Florence; Institute of Biometeorology (M.M., L.M., G.M.), National Research Council, Florence; and Department of Clinical Medicine, Prevention, and Applied Biotechnologies (A.G., G.B., G.C., L.L., G.M., G.P.), University of Milano-Bicocca and Istituto Auxologico Italiano, Milan, Italy.
  • Gianluca Caldara
    From the Clinica Medica Generale e Cardiologia (P.A.M., I.B., G.P., C.L., G.F.G.) and Interdepartmental Centre of Bioclimatology (P.A.M., M.M., S.O., G.M., G.F.G.), University of Florence, Florence; Institute of Biometeorology (M.M., L.M., G.M.), National Research Council, Florence; and Department of Clinical Medicine, Prevention, and Applied Biotechnologies (A.G., G.B., G.C., L.L., G.M., G.P.), University of Milano-Bicocca and Istituto Auxologico Italiano, Milan, Italy.
  • Laura Lonati
    From the Clinica Medica Generale e Cardiologia (P.A.M., I.B., G.P., C.L., G.F.G.) and Interdepartmental Centre of Bioclimatology (P.A.M., M.M., S.O., G.M., G.F.G.), University of Florence, Florence; Institute of Biometeorology (M.M., L.M., G.M.), National Research Council, Florence; and Department of Clinical Medicine, Prevention, and Applied Biotechnologies (A.G., G.B., G.C., L.L., G.M., G.P.), University of Milano-Bicocca and Istituto Auxologico Italiano, Milan, Italy.
  • Simone Orlandini
    From the Clinica Medica Generale e Cardiologia (P.A.M., I.B., G.P., C.L., G.F.G.) and Interdepartmental Centre of Bioclimatology (P.A.M., M.M., S.O., G.M., G.F.G.), University of Florence, Florence; Institute of Biometeorology (M.M., L.M., G.M.), National Research Council, Florence; and Department of Clinical Medicine, Prevention, and Applied Biotechnologies (A.G., G.B., G.C., L.L., G.M., G.P.), University of Milano-Bicocca and Istituto Auxologico Italiano, Milan, Italy.
  • Giampiero Maracchi
    From the Clinica Medica Generale e Cardiologia (P.A.M., I.B., G.P., C.L., G.F.G.) and Interdepartmental Centre of Bioclimatology (P.A.M., M.M., S.O., G.M., G.F.G.), University of Florence, Florence; Institute of Biometeorology (M.M., L.M., G.M.), National Research Council, Florence; and Department of Clinical Medicine, Prevention, and Applied Biotechnologies (A.G., G.B., G.C., L.L., G.M., G.P.), University of Milano-Bicocca and Istituto Auxologico Italiano, Milan, Italy.
  • Giuseppe Mancia
    From the Clinica Medica Generale e Cardiologia (P.A.M., I.B., G.P., C.L., G.F.G.) and Interdepartmental Centre of Bioclimatology (P.A.M., M.M., S.O., G.M., G.F.G.), University of Florence, Florence; Institute of Biometeorology (M.M., L.M., G.M.), National Research Council, Florence; and Department of Clinical Medicine, Prevention, and Applied Biotechnologies (A.G., G.B., G.C., L.L., G.M., G.P.), University of Milano-Bicocca and Istituto Auxologico Italiano, Milan, Italy.
  • Gian Franco Gensini
    From the Clinica Medica Generale e Cardiologia (P.A.M., I.B., G.P., C.L., G.F.G.) and Interdepartmental Centre of Bioclimatology (P.A.M., M.M., S.O., G.M., G.F.G.), University of Florence, Florence; Institute of Biometeorology (M.M., L.M., G.M.), National Research Council, Florence; and Department of Clinical Medicine, Prevention, and Applied Biotechnologies (A.G., G.B., G.C., L.L., G.M., G.P.), University of Milano-Bicocca and Istituto Auxologico Italiano, Milan, Italy.
  • Gianfranco Parati
    From the Clinica Medica Generale e Cardiologia (P.A.M., I.B., G.P., C.L., G.F.G.) and Interdepartmental Centre of Bioclimatology (P.A.M., M.M., S.O., G.M., G.F.G.), University of Florence, Florence; Institute of Biometeorology (M.M., L.M., G.M.), National Research Council, Florence; and Department of Clinical Medicine, Prevention, and Applied Biotechnologies (A.G., G.B., G.C., L.L., G.M., G.P.), University of Milano-Bicocca and Istituto Auxologico Italiano, Milan, Italy.

書誌事項

タイトル別名
  • Effects of Age and Implications for Hypertension Management

抄録

<jats:p> A downward titration of antihypertensive drug regimens in summertime is often performed on the basis of seasonal variations of clinic blood pressure (BP). However, little is known about the actual interaction between outdoor air temperature and the effects of antihypertensive treatment on ambulatory BP. The combined effects of aging, treatment, and daily mean temperature on clinic and ambulatory BP were investigated in 6404 subjects referred to our units between October 1999 and December 2003. Office and mean 24-hour systolic BP, as well as morning pressure surge, were significantly lower in hot (>90th percentiles of air temperature; 136±19, 130±14, and 33.3±16.1 mm Hg; <jats:italic>P</jats:italic> <0.05 for all), and higher in cold (<10th percentiles) days (141±12, 133±11, and 37.3±9.5 mm Hg; at least <jats:italic>P</jats:italic> <0.05 for all) when compared with intermediate days (138±18, 132±14, and 35.3±15.4 mm Hg). At regression analysis, 24-hour and daytime systolic pressure were inversely related to temperature ( <jats:italic>P</jats:italic> <0.01 for all). Conversely, nighttime systolic pressure was positively related to temperature ( <jats:italic>P</jats:italic> <0.02), with hot days being associated with higher nighttime pressure. Air temperature was identified as an independent predictor of nighttime systolic pressure increase in the group of elderly treated hypertensive subjects only. No significant relationship was found between air temperature and heart rate. Our results show for the first time that hot weather is associated with an increase in systolic pressure at night in treated elderly hypertensive subjects. This may be because of a nocturnal BP escape from the effects of a lighter summertime drug regimen and may have important implications for seasonal modulation of antihypertensive treatment. </jats:p>

収録刊行物

  • Hypertension

    Hypertension 47 (2), 155-161, 2006-02

    Ovid Technologies (Wolters Kluwer Health)

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