Excitatory and Inhibitory Effects of Serotonin on Sensorimotor Reactivity Measured with Acoustic Startle
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- Michael Davis
- Department of Psychiatry, Yale University School of Medicine and Connecticut Mental Health Center, New Haven 06508
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- David I. Strachan
- Department of Psychiatry, Yale University School of Medicine and Connecticut Mental Health Center, New Haven 06508
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- Elizabeth Kass
- Department of Psychiatry, Yale University School of Medicine and Connecticut Mental Health Center, New Haven 06508
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説明
<jats:p>Serotonin infused into the lateral ventricle in rats produced a dose-dependent depression of the acoustic startle reflex. When infused onto the spinal cord, serotonin produced a dose-dependent increase in startle. Thus the same neurotransmitter can modulate the same behavior in opposite ways, depending on which part of the central nervous system is involved.</jats:p>
収録刊行物
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- Science
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Science 209 (4455), 521-523, 1980-07-25
American Association for the Advancement of Science (AAAS)