-
- Gail Ishiyama
- Department of Neurology Reed Neurological Research Center David Geffen School of Medicine at UCLA Los Angeles California
-
- Ivan A. Lopez
- Department of Head and Neck Surgery Department of Surgery David Geffen School of Medicine at UCLA Los Angeles California
-
- Ali R. Sepahdari
- Department of Radiology David Geffen School of Medicine at UCLA Los Angeles California
-
- Akira Ishiyama
- Department of Head and Neck Surgery Department of Surgery David Geffen School of Medicine at UCLA Los Angeles California
書誌事項
- 公開日
- 2015-03-12
- 権利情報
-
- http://onlinelibrary.wiley.com/termsAndConditions#vor
- DOI
-
- 10.1111/nyas.12699
- 公開者
- Wiley
この論文をさがす
説明
<jats:p>Meniere's disease is a poorly understood, disabling syndrome causing spells of vertigo, hearing fluctuation, tinnitus, and aural fullness. In this paper, we present a review of the histopathology, cytochemistry, and imaging of Meniere's disease. Histopathology is significant for neuroepithelial damage with hair cell loss, basement membrane thickening, and perivascular microvascular damage. Cytochemical alterations are significant for altered AQP4 and AQP6 expression in the supporting cell, and altered cochlin and mitochondrial protein expression. Current developments include imaging techniques to determine the degree and presence of endolymphatic hydrops, and future studies will endeavor to correlate the observance of hydrops with clinical findings.</jats:p>
収録刊行物
-
- Annals of the New York Academy of Sciences
-
Annals of the New York Academy of Sciences 1343 (1), 49-57, 2015-03-12
Wiley