Efficient Synthesis of the Peptide Fragment of the Natural Depsipeptides Jaspamide and Chondramide

  • Danil P. Zarezin
    Department of Chemistry Lomonosov Moscow State University 119991 Moscow Russia
  • Olga I. Shmatova
    Department of Chemistry Lomonosov Moscow State University 119991 Moscow Russia
  • Adil M. Kabylda
    Department of Chemistry Lomonosov Moscow State University 119991 Moscow Russia
  • Valentine G. Nenajdenko
    Department of Chemistry Lomonosov Moscow State University 119991 Moscow Russia

書誌事項

公開日
2018-08-21
権利情報
  • http://onlinelibrary.wiley.com/termsAndConditions#vor
DOI
  • 10.1002/ejoc.201800992
公開者
Wiley

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説明

<jats:p>A new method for the synthesis of the tripeptide part of the jaspamide and chondramide alkaloids using a Ugi reaction was developed. The reported approach is considerably shorter than all literature syntheses of the peptide parts of these natural products. A family of peptides with different substituents at the 2‐position of the indole moiety was prepared to open up access to analogues of these natural products.</jats:p>

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