A case of successful treatment of cutaneous <i>Acanthamoeba</i> infection in a lung transplant recipient

書誌事項

公開日
2007-02-21
権利情報
  • http://onlinelibrary.wiley.com/termsAndConditions#vor
DOI
  • 10.1111/j.1399-3062.2006.00159.x
公開者
Wiley

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説明

<jats:p><jats:bold>Abstract: </jats:bold> <jats:italic>Acanthamoeba</jats:italic> species are known to cause 2 well‐described entities: (1) granulomatous amoebic encephalitis (GAE), which usually affects immunocompromised hosts, and (2) keratitis, which typically follows trauma associated with contamination of water or contact lenses. Less common manifestations include pneumonitis and a subacute granulomatous dermatitis. We describe a case of granulomatous dermatitis secondary to <jats:italic>Acanthamoeba</jats:italic> infection in a lung transplant recipient and a successful outcome following treatment with lipid formulation of amphotericin B and voriconazole. We believe this is the second case report describing disseminated <jats:italic>Acanthamoeba</jats:italic> infection in a lung transplant recipient. We also describe successful outcome with a combination of lipid formulation of amphotericin B and voriconazole, drugs that have not been previously reported to treat <jats:italic>Acanthamoeba</jats:italic>.</jats:p>

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