Cryogenic oven-trapping gas chromatography for analysis of volatile organic compounds in body fluids

書誌事項

公開日
2002-02-19
権利情報
  • http://www.springer.com/tdm
DOI
  • 10.1007/s00216-002-1240-z
公開者
Springer Science and Business Media LLC

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説明

Cryogenic oven-trapping (COT) with capillary GC has been successfully applied to analysis of chloroform, dichloromethane, trichloroethylene, diethyl ether, the components of solvent thinner (ethyl acetate, benzene, n-butanol, toluene, and others), xylene isomers, cyanide, ethanol, hexanes, general anesthetics, and styrene in human body fluids. This COT-GC technique was compared with headspace solid-phase microextraction (SPME) coupled with GC for some volatile organic compounds (VOC); for all compounds compared the sensitivity achieved using COT-GC was more than ten times higher than for headspace SPME-GC. The COT-GC method is recommended for widespread use in forensic and environmental toxicology, because it is simple, requires no special GC operations, and yet enables high sensitivity and high resolution.

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