<jats:title>Abstract</jats:title><jats:sec><jats:title>Introduction</jats:title><jats:p>Computerized pneumatic cuff pressure algometry (<jats:styled-content style="fixed-case">CPA</jats:styled-content>) using the DoloCuff is a new method for pain assessment. Intra‐ and inter‐rater reliabilities have not yet been established. Our aim was to examine the inter‐ and intrarater reliabilities of DoloCuff measures in healthy subjects.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>Twenty healthy subjects (ages 20 to 29 years) were assessed three times at 24‐hour intervals by two trained raters. Inter‐rater reliability was established based on the first and second assessments, whereas intrarater reliability was based on the second and third assessments. Subjects were randomized 1:1 to first assessment at either rater 1 or rater 2. The variables of interest were pressure pain threshold (<jats:styled-content style="fixed-case">PT</jats:styled-content>), pressure pain tolerance (<jats:styled-content style="fixed-case">PT</jats:styled-content>ol), and temporal summation index (<jats:styled-content style="fixed-case">TSI</jats:styled-content>). Reliability was estimated by a two‐way mixed intraclass correlation coefficient (<jats:styled-content style="fixed-case">ICC</jats:styled-content>) absolute agreement analysis. Reliability was considered excellent if <jats:styled-content style="fixed-case">ICC</jats:styled-content> > 0.75, fair to good if 0.4 < <jats:styled-content style="fixed-case">ICC</jats:styled-content> < 0.75, and poor if <jats:styled-content style="fixed-case">ICC</jats:styled-content> < 0.4. Bias and random errors between raters and assessments were evaluated using 95% confidence interval (<jats:styled-content style="fixed-case">CI</jats:styled-content>) and Bland–Altman plots.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Inter‐rater reliability for <jats:styled-content style="fixed-case">PT</jats:styled-content>,<jats:styled-content style="fixed-case"> PT</jats:styled-content>ol, and <jats:styled-content style="fixed-case">TSI</jats:styled-content> was 0.88 (95% <jats:styled-content style="fixed-case">CI</jats:styled-content>: 0.69 to 0.95), 0.86 (95% <jats:styled-content style="fixed-case">CI</jats:styled-content>: 0.65 to 0.95), and 0.81 (95% <jats:styled-content style="fixed-case">CI</jats:styled-content>: 0.42 to 0.94), respectively. The intrarater reliability for <jats:styled-content style="fixed-case">PT</jats:styled-content>,<jats:styled-content style="fixed-case"> PT</jats:styled-content>ol, and <jats:styled-content style="fixed-case">TSI</jats:styled-content> was 0.81 (95% <jats:styled-content style="fixed-case">CI</jats:styled-content>: 0.53 to 0.92), 0.89 (95% <jats:styled-content style="fixed-case">CI</jats:styled-content>: 0.74 to 0.96), and 0.75 (95% <jats:styled-content style="fixed-case">CI</jats:styled-content>: 0.28 to 0.91), respectively.</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>Inter‐rater reliability was excellent for <jats:styled-content style="fixed-case">PT</jats:styled-content>,<jats:styled-content style="fixed-case"> PT</jats:styled-content>ol, and <jats:styled-content style="fixed-case">TSI</jats:styled-content>. Similarly, the intrarater reliability for <jats:styled-content style="fixed-case">PT</jats:styled-content> and <jats:styled-content style="fixed-case">PT</jats:styled-content>ol was excellent, while borderline excellent/good for <jats:styled-content style="fixed-case">TSI</jats:styled-content>. Therefore, the DoloCuff can be used to obtain reliable measures of pressure pain parameters in healthy subjects.</jats:p></jats:sec>