Prothrombin Complex Concentrates in Trauma and Perioperative Bleeding

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  • Oliver Grottke
    From the Department of Anaesthesiology, RWTH Aachen University Hospital, Aachen, Germany (O.G.); and Department of Anesthesiology, Duke University School of Medicine, Durham, North Carolina (J.H.L.).
  • Jerrold H. Levy
    From the Department of Anaesthesiology, RWTH Aachen University Hospital, Aachen, Germany (O.G.); and Department of Anesthesiology, Duke University School of Medicine, Durham, North Carolina (J.H.L.).

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<jats:title>Abstract</jats:title> <jats:p>There is increasing interest in prothrombin complex concentrates as therapy for perioperative and trauma-related bleeding. A suitable point-of-care test is needed to guide such therapy, and randomized controlled trials are needed for robust, evidence-based recommendations.</jats:p>

Journal

  • Anesthesiology

    Anesthesiology 122 (4), 923-931, 2015-04

    Ovid Technologies (Wolters Kluwer Health)

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