Discovery of Novel Topoisomerase II Inhibitors by Medicinal Chemistry Approaches

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  • Wei Hu
    State Key Laboratory of Microbial Technology, School of Life Science, Shandong University, 27 South Shanda Road, 250100 Ji’nan, Shandong, P. R. China
  • Xu-Sheng Huang
    Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Science and Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, China
  • Ji-Feng Wu
    Institute of Criminal Science and Technology, Ji’nan Public Security Bureau, 21 South QiliShan Road, 250000 Ji’nan, Shandong, P. R. China
  • Liang Yang
    Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, 44 West Culture Road, 250012, Ji’nan, Shandong, P. R. China
  • Yong-Tang Zheng
    Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Science and Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, China
  • Yue-Mao Shen
    Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, 44 West Culture Road, 250012, Ji’nan, Shandong, P. R. China
  • Zhi-Yu Li
    Department of Pharmaceutical Sciences, Philadelphia College of Pharmacy, Philadelphia, Pennsylvania 19104, United States
  • Xun Li
    Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, 44 West Culture Road, 250012, Ji’nan, Shandong, P. R. China

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