High dose rate prostate brachytherapy: an overview of the rationale, experience and emerging applications in the treatment of prostate cancer

  • A Challapalli
    Department of Clinical Oncology, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, UK
  • E Jones
    Department of Radiotherapy Physics and Radiobiology, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, UK
  • C Harvey
    Department of Radiology, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, UK
  • G O Hellawell
    Department of Urology, Northwick Park Hospital, North West London Hospitals NHS Trust, London, UK
  • S A Mangar
    Department of Clinical Oncology, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, UK

書誌事項

公開日
2012-11-01
権利情報
  • https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model
DOI
  • 10.1259/bjr/15403217
公開者
Oxford University Press (OUP)

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説明

<jats:p>The technological advances in real-time ultrasound image guidance for high dose rate (HDR) prostate brachytherapy places this treatment modality at the forefront of innovation in radiotherapy. This review article will explore the rationale for HDR brachytherapy as a highly conformal method of dose delivery and safe dose escalation to the prostate, in addition to the particular radiobiological advantages it has over low dose rate and external beam radiotherapy. The encouraging outcome data and favourable toxicity profile will be discussed before looking at emerging applications for the future and how this procedure will feature alongside stereotactic radiosurgery.</jats:p>

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