Risk factors for small for gestational age

書誌事項

公開日
2007-10-31
権利情報
  • http://onlinelibrary.wiley.com/termsAndConditions#vor
DOI
  • 10.1111/j.1442-200x.2007.02494.x
公開者
Wiley

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説明

<jats:title>Abstract</jats:title><jats:p><jats:bold>Background: </jats:bold> The purpose of the paper was to determine the risk factors for small‐for‐gestational‐age (SGA) infants at full term, in Japan.</jats:p><jats:p><jats:bold>Methods: </jats:bold> The study was conducted at four hospitals and clinics in the Tokyo metropolitan area. A retrospective review of 2972 mothers and their infants born from singleton pregnancies at any time during the years 2002 and 2003 was conducted.</jats:p><jats:p><jats:bold>Results: </jats:bold> Of these women, 8.4% gave birth to SGA infants. The proportion of SGA infants was significantly higher among heavy smokers (>10 cigarettes/day; 13.7%, <jats:italic>P</jats:italic> < 0.01). The odds ratio (OR) for SGA decreased significantly in proportion to the pregnancy body mass index (OR, 0.89; 95% confidence interval [CI]: 0.84–0.94, <jats:italic>P</jats:italic> < 0.001). The OR of SGA for stratified maternal weight gain was 1.79 (95%CI: 1.24–2.58, <jats:italic>P</jats:italic> ≤ 0.01) for weight gain < 8.0 kg; 1.16 (95%CI: 0.79–1.71, <jats:italic>P</jats:italic> = 0.45) for weight gain 8.0–10.0 kg; and 0.49 (95%CI: 0.3–0.78, <jats:italic>P</jats:italic> < 0.01) for weight gain >12 kg.</jats:p><jats:p><jats:bold>Conclusion: </jats:bold> The present study clearly confirms the detrimental effect of a low prepregnancy body mass index, low maternal weight gain and maternal smoking during pregnancy on the incidence of SGA infants.</jats:p>

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